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Simultaneous UV Estimation of Antihypertesive Drugs: Determination of Amlodipine Besylate, Olmesartan Medoxomil and Hydrochlorthiazide in Tablet Dosage Form - Couverture souple

Sharma, Hemendra Kumar; Jain, Nilesh; Jain, Surendra

 
9783846583081: Simultaneous UV Estimation of Antihypertesive Drugs: Determination of Amlodipine Besylate, Olmesartan Medoxomil and Hydrochlorthiazide in Tablet Dosage Form
Couverture souple
ISBN 10 : 3846583081 ISBN 13 : 9783846583081
Editeur : LAP LAMBERT Academic Publishing, 2012

Synopsis

A new, simple, accurate, precise and reproducible UV spectrophotometric method is being developed for the simultaneous estimation of amlodipine besylate, olmesartan medoxomil and hydrochlorthiazide in tablet dosage form. The stock solutions were prepared in methanol. The λmax for amlodipine besylate, olmesartan medoxomil and hydrochlorthiazide were 238.5nm, 256.5nm and 271.5nm respectively. The amlodipine besylate, olmesartan medoxomil and hydrochlorthiazide obeyed Beer’s law in concentration range of 5-25µg/ml, 6-30µg/ml and 5-25µg/ml respectively. Results of analysis of simultaneous equation method were analyzed and validated for various parameters according to ICH guidelines.

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Présentation de l'éditeur

A new, simple, accurate, precise and reproducible UV spectrophotometric method is being developed for the simultaneous estimation of amlodipine besylate, olmesartan medoxomil and hydrochlorthiazide in tablet dosage form. The stock solutions were prepared in methanol. The λmax for amlodipine besylate, olmesartan medoxomil and hydrochlorthiazide were 238.5nm, 256.5nm and 271.5nm respectively. The amlodipine besylate, olmesartan medoxomil and hydrochlorthiazide obeyed Beer’s law in concentration range of 5-25µg/ml, 6-30µg/ml and 5-25µg/ml respectively. Results of analysis of simultaneous equation method were analyzed and validated for various parameters according to ICH guidelines.

Biographie de l'auteur

Mr. Hemendra Kumar Sharma has obtained M. Pharm degree in Pharmaceutical Chemistry in 2011. Since he has published three international and ten national research article in reputed journals in field of analysis and he has also obtained scientific credit from international journal.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2012
Langue
anglais
ISBN 10 
3846583081
ISBN 13 
9783846583081
Reliure
Broché
Nombre de pages
128
Coordonnées du fabricant
non disponible
Personne responsable
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