Eco-Genetic Investigation of Neural Tube Defects: North Indian Population - Couverture souple

Vats, Rajeev; Sharma, Rajneesh Kumar; Vats, Laxmi Kant

 
9783847306771: Eco-Genetic Investigation of Neural Tube Defects: North Indian Population

Synopsis

The neural tube defects observed during the present investigation revealed a spectrum of congenital abnormalities such as spina bifida, meningocele, meningomyelocele, lipomeningocele and encephalocele with variable clinical and morphological presentations. The epidemiological factors like maternal age, abortion (induced or spontaneous), parity, nutrition, occupation, habitation, smoking/alcoholic, medication and sex of the proband have been analyzed. Biochemically, the variations in the blood serum protein fractions of proband and their mothers were investigated. Variations in the concentrations of trace elements viz. Cu, Zn, Mn, Fe and Se in blood, cell mass and serum of both mother and proband were estimated. The data collected on different epidemiological and biochemical factors have been statistically analyzed. The information generated in this study has been discussed with special emphasis on diagnostics and screening of neural tube defects.

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Présentation de l'éditeur

The neural tube defects observed during the present investigation revealed a spectrum of congenital abnormalities such as spina bifida, meningocele, meningomyelocele, lipomeningocele and encephalocele with variable clinical and morphological presentations. The epidemiological factors like maternal age, abortion (induced or spontaneous), parity, nutrition, occupation, habitation, smoking/alcoholic, medication and sex of the proband have been analyzed. Biochemically, the variations in the blood serum protein fractions of proband and their mothers were investigated. Variations in the concentrations of trace elements viz. Cu, Zn, Mn, Fe and Se in blood, cell mass and serum of both mother and proband were estimated. The data collected on different epidemiological and biochemical factors have been statistically analyzed. The information generated in this study has been discussed with special emphasis on diagnostics and screening of neural tube defects.

Biographie de l'auteur

Dr. Rajeev Vats has obtained his Ph.D. degree in Zoology from Kurukshetra University, Kurukshetra in 2000. Since than he has worked at various positions in State Government of Haryana. He has published several articles in the reputed journals. Presently he is working as Senior Faculty with The University of Dodoma,Dodoma Tanzania.

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