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Protein Folding and Aggregation: Unfolding of Hen Egg White Lysozyme - Couverture souple

Hameed, Mahrukh; Fazili, Khalid Majid

 
9783847307914: Protein Folding and Aggregation: Unfolding of Hen Egg White Lysozyme
Couverture souple
ISBN 10 : 3847307916 ISBN 13 : 9783847307914
Editeur : LAP LAMBERT Academic Publishing, 2011

Synopsis

Built from a set of twenty standard amino acids, Proteins, the most abundant biological macromolecules found in living cells have great structural and functional diversity. Initially synthesized as linear polypeptide chains, they are required to fold to their unique native formats to gain function. Losing track during the folding process, proteins may misfold and end up as aggregates, causing neurodegenerative disorders. This book provides an overview of the protein folding scenario, the models and theories proposed, and consequences of misfolding have been discussed The book also provides a detailed in vitro study of the pH and solvent induced unfolding and aggregation of Hen Egg White Lysozyme. Evidence is presented for the presence of molten globule like intermediate at high pH and t-butanol induced amyloid like structure.

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Présentation de l'éditeur

Built from a set of twenty standard amino acids, Proteins, the most abundant biological macromolecules found in living cells have great structural and functional diversity. Initially synthesized as linear polypeptide chains, they are required to fold to their unique native formats to gain function. Losing track during the folding process, proteins may misfold and end up as aggregates, causing neurodegenerative disorders. This book provides an overview of the protein folding scenario, the models and theories proposed, and consequences of misfolding have been discussed The book also provides a detailed in vitro study of the pH and solvent induced unfolding and aggregation of Hen Egg White Lysozyme. Evidence is presented for the presence of molten globule like intermediate at high pH and t-butanol induced amyloid like structure.

Biographie de l'auteur

Dr Mahrukh Hamid, Ph.D (Biochemistry), University of Kashmir, Srinagar is currently working at SK Institute of Medical Sciences, Srinagar, India. She has many international publications to her credit. Dr. Khalid M Fazili, Associate Professor, Biotechnology, University of Kashmir, Srinagar, India has authored several reviews and many research papers

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2011
Langue
anglais
ISBN 10 
3847307916
ISBN 13 
9783847307914
Reliure
Broché
Nombre de pages
112
Coordonnées du fabricant
non disponible
Personne responsable
Buchpark GmbH
gpsr@buchpark.de

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Trebbin
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