Computational Prediction of Protein-Protein Interaction: Domain information based protein-protein interaction prediction technique - Couverture souple

Barman, Ranjan Kumar; Mukhopadhyay, Anirban

 
9783847319399: Computational Prediction of Protein-Protein Interaction: Domain information based protein-protein interaction prediction technique

Synopsis

Protein-protein interactions are extremely valuable towards protein functions and cellular processes or we can say that protein-protein interactions play an important role in living cells. Therefore, if we can control the interactions between proteins, as a result, we can control some functionality of cells. Main functionality of a protein is carried out by its domains. So, domain is a structural or/and functional unit of protein. Behind protein-protein interactions there exist some domain-domain interactions. Therefore, under standing protein-protein interaction at domain level gives a global view of protein-protein interaction network.In this book, we have made an attempt to infer domain-domain interactions from interacting and non-interacting protein pairs then we have predicted protein-protein interactions based on inferred domain-domain interactions.

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Présentation de l'éditeur

Protein-protein interactions are extremely valuable towards protein functions and cellular processes or we can say that protein-protein interactions play an important role in living cells. Therefore, if we can control the interactions between proteins, as a result, we can control some functionality of cells. Main functionality of a protein is carried out by its domains. So, domain is a structural or/and functional unit of protein. Behind protein-protein interactions there exist some domain-domain interactions. Therefore, under standing protein-protein interaction at domain level gives a global view of protein-protein interaction network.In this book, we have made an attempt to infer domain-domain interactions from interacting and non-interacting protein pairs then we have predicted protein-protein interactions based on inferred domain-domain interactions.

Biographie de l'auteur

Ranjan Kumar Barman has done his M.Tech in Comp. Sc. & Engg.from University of Kalyani,India.His research interests include data mining,bio-informatics etc.Dr. Anirban Mukhopadhyay has done his PhD from JU,India.His research interests include soft computing,data mining etc.He is currently working as an Assistant Professor in University of Kalyani.

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