Evolutionary Analysis of Plants Using Chloroplast Proteome Sequences: Method to detect unbiased conservation between genomes - Couverture souple

Shanker, Asheesh; SHARMA, VINAY

 
9783847375630: Evolutionary Analysis of Plants Using Chloroplast Proteome Sequences: Method to detect unbiased conservation between genomes

Synopsis

As more chloroplast genomes are sequenced their comparative analysis helps to identify conservedness between genomes and provide evidence on the evolutionary history of organisms. In order to increase the significance of similarity search, we defined three new parameters; Cumulative Sum of Homologs (CSH), Actual Proportion of Homologs (APH) and Homology Impact (HI) for post BLAST analysis. These parameters can also be used in other similarity search tools and are useful to identify unbiased conservation between genomes. Moreover, our work demonstrates use of missing data in phylogenetic analysis. The trees obtained from incomplete data sets have higher levels of bootstrap support for most of the nodes in comparison to the tree from complete data set. Further, comparative analysis of chloroplast proteomes identified hornworts as the transition link between bryophytes and pteridophytes.

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Présentation de l'éditeur

As more chloroplast genomes are sequenced their comparative analysis helps to identify conservedness between genomes and provide evidence on the evolutionary history of organisms. In order to increase the significance of similarity search, we defined three new parameters; Cumulative Sum of Homologs (CSH), Actual Proportion of Homologs (APH) and Homology Impact (HI) for post BLAST analysis. These parameters can also be used in other similarity search tools and are useful to identify unbiased conservation between genomes. Moreover, our work demonstrates use of missing data in phylogenetic analysis. The trees obtained from incomplete data sets have higher levels of bootstrap support for most of the nodes in comparison to the tree from complete data set. Further, comparative analysis of chloroplast proteomes identified hornworts as the transition link between bryophytes and pteridophytes.

Biographie de l'auteur

Dr. Asheesh Shanker is actively involved in bioinformatics teaching and research at Dept. of Bioscience and Biotechnology, Banasthali University, India. Earlier he co-authored text book of bioinformatics with Prof. Sharma. Prof. Vinay Sharma, Dean & Chair of the same department has contributed through his decades of teaching and research expertise.

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