Effect Of Different Calcium Channel Blockers on Gastric Ulcers: Effect Of Calcium Channel Blockers On Ulcers - Couverture souple

Jha, Shailendra Kumar; Jadhav, Anil; Harshadrai, Merai Ankit

Couverture souple

ISBN 10 : 3847376543 ISBN 13 : 9783847376545

Editeur : LAP LAMBERT Academic Publishing, 2012

Synopsis

Background & Objective: Since calcium has got importance in physiology and the objective of the present study is to study the effect of different calcium channel blockers through i.c.v administration on gastric and duodenal ulcers. Methods: The effect of different calcium channel blockers on gastric and duodenal ulcers were evaluated by using different experimental models such as acetic acid induced chronic gastric ulcer, pylorus ligation induced gastric ulcers, ethanol induced gastric ulcers, stress induced gastric ulcers, and cysteamine induced duodenal ulcers. In all these models the common parameter determined was ulcer index. Results: The nickel salt and verapamil a significant effect on ulcer healing in acetic acid induced ulcer model, ω-agatoxin did not show any significant effect on ulcer healing. The treatment groups showed a significant reduction in ulcer index in other models. Only ω-agatoxin did not showed significant increase in mucin compared to other treatment groups.

Détails de l'édition

• Éditeur: LAP LAMBERT Academic Publishing
• Date d'édition: 2012
• Langue: anglais
• ISBN 10: 3847376543
• ISBN 13: 9783847376545
• Reliure: Broché
• Nombre de pages: 56
• Coordonnées du fabricant: non disponible
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