Articles liés à Applications of Liquid Chromatography-Mass Spectrometry...

Applications of Liquid Chromatography-Mass Spectrometry in Bioassays: An experimental approach - Couverture souple

Shinde, Dhananjay D.

 
9783848401116: Applications of Liquid Chromatography-Mass Spectrometry in Bioassays: An experimental approach
Couverture souple
ISBN 10 : 3848401118 ISBN 13 : 9783848401116
Editeur : LAP LAMBERT Academic Publishing, 2012

Synopsis

Drug discovery is a complex and interdisciplinary research, often with conflicting goals and a complex large data used for the development of a balanced clinical candidate. Written from the perspective of drug discovery, it is a practical guide for the analyst and ADME scientists and advanced students in this field. Separate chapters discuss each important aspect, covering the fundamental concepts of separation science, mass spectrometry and pharmacokinetic (PK) studies discussed with minimum mathematical equations. The present book provides in-hand solutions for offline and online sample extraction methods, column switching techniques, chiral separations and validation of the optimized methods as per the standard protocol and FDA guidelines. With practical details obtained in analytical laboratory…synthesis of drug metabolites and related substances, their characterization, separation, validation and applications in PK studies, book provides a successful approach to design, planning, execution and interpretation of research studies. This book will serve as a practical reference in regular use for researchers and scientist interested in drug discovery.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Drug discovery is a complex and interdisciplinary research, often with conflicting goals and a complex large data used for the development of a balanced clinical candidate. Written from the perspective of drug discovery, it is a practical guide for the analyst and ADME scientists and advanced students in this field. Separate chapters discuss each important aspect, covering the fundamental concepts of separation science, mass spectrometry and pharmacokinetic (PK) studies discussed with minimum mathematical equations. The present book provides in-hand solutions for offline and online sample extraction methods, column switching techniques, chiral separations and validation of the optimized methods as per the standard protocol and FDA guidelines. With practical details obtained in analytical laboratory...synthesis of drug metabolites and related substances, their characterization, separation, validation and applications in PK studies, book provides a successful approach to design, planning, execution and interpretation of research studies. This book will serve as a practical reference in regular use for researchers and scientist interested in drug discovery.

Biographie de l'auteur

Dhananjay D. Shinde, M.Sc., Ph.D.: Studied at Indian Institute of Chemical Technology and Osmania University, Hyderabad, India. Postdoctoral Research Fellow at Inje University College of Medicine, Busan Paik Hospital, Busan, S. Korea

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2012
Langue
anglais
ISBN 10 
3848401118
ISBN 13 
9783848401116
Reliure
Broché
Nombre de pages
224
Coordonnées du fabricant
non disponible
Personne responsable
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