Biofunctionalized Magnetic Nanoparticles for Cancer Theragnostics: Design,Synthesis and Biofunctionalization of Magnetic Nanoparticles for Targeted Cancer Therapy and Diagnostic Imaging - Couverture souple

Das, Manasmita; Basak, Amit; Pramanik, Panchanan

 
9783848406319: Biofunctionalized Magnetic Nanoparticles for Cancer Theragnostics: Design,Synthesis and Biofunctionalization of Magnetic Nanoparticles for Targeted Cancer Therapy and Diagnostic Imaging
Couverture souple
ISBN 10 : 3848406314 ISBN 13 : 9783848406319
Editeur : LAP LAMBERT Academic Publishing, 2012

Synopsis

Superparamagnetic iron-oxide nanoparticles with tailored surface chemistry may be regarded as one of the most popular multifunctional materials for biomedical applications. Their unique capabilities to enhance the proton relaxation of specific tissues, coupled with outstanding magnetic manipulability make them highly promising probes/ vectors for magnetic resonance imaging (MRI) contrast enhancement, magnetic fluid hyperthermia (MFH) for selective destruction of cancer cells and magnetically modulated drug or gene delivery. The present study contributes some new tool-boxes for the facile, water-based synthesis of biocompatible coating-stabilized multifunctional iron-oxide nanoparticles (MNPs), simultaneously integrated with fluorophores, targeting agents and/ or chemotherapeutic drugs. Herein, we describe some novel strategies to design and synthesize theragnostic MNPs that can simultaneously trace, target and kill cancer cells while allowing a real time monitoring of drug delivery through combined MR and fluorescence imaging.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Superparamagnetic iron-oxide nanoparticles with tailored surface chemistry may be regarded as one of the most popular multifunctional materials for biomedical applications. Their unique capabilities to enhance the proton relaxation of specific tissues, coupled with outstanding magnetic manipulability make them highly promising probes/ vectors for magnetic resonance imaging (MRI) contrast enhancement, magnetic fluid hyperthermia (MFH) for selective destruction of cancer cells and magnetically modulated drug or gene delivery. The present study contributes some new tool-boxes for the facile, water-based synthesis of biocompatible coating-stabilized multifunctional iron-oxide nanoparticles (MNPs), simultaneously integrated with fluorophores, targeting agents and/ or chemotherapeutic drugs. Herein, we describe some novel strategies to design and synthesize theragnostic MNPs that can simultaneously trace, target and kill cancer cells while allowing a real time monitoring of drug delivery through combined MR and fluorescence imaging.

Biographie de l'auteur

Dr. Manasmita Das pursued her PhD in Chemistry from IIT Kharagpur under the joint supervision of Prof. Amit Basak and Prof. Panchanan Pramanik. Currently, she is working as a postdoctoral fellow in NIPER Mohali under Dr. Sanyog Jain. Her research focuses on the development of "smart", multifunctional nanocarriers for theragnostic applications.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2012
Langue
anglais
ISBN 10 
3848406314
ISBN 13 
9783848406319
Reliure
Broché
Nombre de pages
192
Coordonnées du fabricant
non disponible
Personne responsable
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