UV- Methods for Anti-Hypertensive Drugs Using Hydrotropic Technique: Quantitative estimation of Anti-Hypertensive Drug Combinations using Hydrotropic Solubilization Technique - Couverture souple

Jain, Ruchi; Jain, Nilesh; Jain, Surendra

 
9783848406654: UV- Methods for Anti-Hypertensive Drugs Using Hydrotropic Technique: Quantitative estimation of Anti-Hypertensive Drug Combinations using Hydrotropic Solubilization Technique
Couverture souple
ISBN 10 : 3848406659 ISBN 13 : 9783848406654
Editeur : LAP LAMBERT Academic Publishing, 2012

Synopsis

A successful attempt was made for the spectrophotometric quantitative estimation of two antihypertensive marketed combinations using mixed hydrotropic agent. The method was developed by experimentation based on thorough literature survey and ascertained by statistical parameters of sampling. The entire work was performed on Shimadzu UV/VIS double beam-double detector spectrophotometer (Model-1700 series). The result obtained shows the developed method to be precise, simple, rapid and accurate. Thus these can be used for routine analysis of Eprosartan, Hydrochlorothiazide, and Olmesartan Medoxomil in bulk drug and tablet dosage form instead of processing of extraction using organic solvent separately. It may reduce the large total concentration of hydrotropic agents necessary to produce modest increase in solubility by employing combination of agents in lower concentration. Spectrophotometric precluding the use of organic solvents and thus avoids the problem of residual toxicity, error due to volatility, pollution, cost etc.

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Présentation de l'éditeur

A successful attempt was made for the spectrophotometric quantitative estimation of two antihypertensive marketed combinations using mixed hydrotropic agent. The method was developed by experimentation based on thorough literature survey and ascertained by statistical parameters of sampling. The entire work was performed on Shimadzu UV/VIS double beam-double detector spectrophotometer (Model-1700 series). The result obtained shows the developed method to be precise, simple, rapid and accurate. Thus these can be used for routine analysis of Eprosartan, Hydrochlorothiazide, and Olmesartan Medoxomil in bulk drug and tablet dosage form instead of processing of extraction using organic solvent separately. It may reduce the large total concentration of hydrotropic agents necessary to produce modest increase in solubility by employing combination of agents in lower concentration. Spectrophotometric precluding the use of organic solvents and thus avoids the problem of residual toxicity, error due to volatility, pollution, cost etc.

Biographie de l'auteur

Ruchi Jain passed her M.Tech (Biotech) with Gold Medal from School of Biotech RGPV, Bhopal.Mrs. Jain has more than 7 years of teaching and research experience. She has published about 21 research papers in referred Journals. Presently she is a Professor at Sagar Institute of Research & Technology- Pharmacy, Bhopal.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2012
Langue
anglais
ISBN 10 
3848406659
ISBN 13 
9783848406654
Reliure
Broché
Nombre de pages
128
Coordonnées du fabricant
non disponible
Personne responsable
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