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Antioxidant Activity of Phenolic Compounds in Cell Culture Systems: Exploring phenol oxidases as biocatalysts for better antioxidant activity - Couverture souple

Zwane, Eunice Nonhlanhla Refiloe

 
9783848411320: Antioxidant Activity of Phenolic Compounds in Cell Culture Systems: Exploring phenol oxidases as biocatalysts for better antioxidant activity
Couverture souple
ISBN 10 : 3848411326 ISBN 13 : 9783848411320
Editeur : LAP LAMBERT Academic Publishing, 2012

Synopsis

ROS and their proven involvement in some human physiopathologies have drawn significant interest over the last few decades. Oxidative stress has been associated with many diseases such as cancers. The development of disease can be attributed to the oxidative alteration of molecules such as proteins, lipids, carbohydrates and nucleic acids by ROS. The human body has developed its own defence system to deal with oxidative stress, but certain external factors such as UVR may result in elevated cellular ROS concentrations, overwhelming the body’s defence system thus leading to disease. To neutralize this effect, exogenic antioxidants particularly polyphenols, may be helpful to counteract ROS by preventing oxidation caused by ROS. To assess the antioxidant capacity of selected phenols, polyphenolic compounds were successfully synthesized in this study through biocatalytic reactions using phenol oxidases, to produce natural polyphenols suggested to have higher antioxidant activity than their monomers. Production of natural antioxidants was significantly considered for eventual consumer satisfaction and world market success if putative antioxidant were to go market.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

ROS and their proven involvement in some human physiopathologies have drawn significant interest over the last few decades. Oxidative stress has been associated with many diseases such as cancers. The development of disease can be attributed to the oxidative alteration of molecules such as proteins, lipids, carbohydrates and nucleic acids by ROS. The human body has developed its own defence system to deal with oxidative stress, but certain external factors such as UVR may result in elevated cellular ROS concentrations, overwhelming the body’s defence system thus leading to disease. To neutralize this effect, exogenic antioxidants particularly polyphenols, may be helpful to counteract ROS by preventing oxidation caused by ROS. To assess the antioxidant capacity of selected phenols, polyphenolic compounds were successfully synthesized in this study through biocatalytic reactions using phenol oxidases, to produce natural polyphenols suggested to have higher antioxidant activity than their monomers. Production of natural antioxidants was significantly considered for eventual consumer satisfaction and world market success if putative antioxidant were to go market.

Biographie de l'auteur

Eunice Zwane obtained her MSc degree in Chemical Engineering in 2010 at the University of Cape Town. Since then she has worked as manager at various companies, her specialization being on strategically collecting and analyzing data. She is currently pursuing a PhD degree which focuses on the sustainable development of biofuel in South Africa.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2012
Langue
anglais
ISBN 10 
3848411326
ISBN 13 
9783848411320
Reliure
Broché
Nombre de pages
120
Coordonnées du fabricant
non disponible
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