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Activated Nitriles in Heterocyclic Synthesis: Studies on the Chemistry of N-(cyanoacetyl) aminoantipyrine & antipyrinylhydrazonomalononitrile - Couverture souple

Ahmed, Ramy Rabie Shafek; Fadda, A; Bondock

 
9783848487875: Activated Nitriles in Heterocyclic Synthesis: Studies on the Chemistry of N-(cyanoacetyl) aminoantipyrine & antipyrinylhydrazonomalononitrile
Couverture souple
ISBN 10 : 384848787X ISBN 13 : 9783848487875
Editeur : LAP LAMBERT Academic Publishing, 2012

Synopsis

The introduction part in this work presents a systematic and comprehensive survey of the methods of preparation and the chemical reactivity of cyanoacetamide derivatives. These compounds are important intermediates for the synthesis of a variety of otherwise difficulty accessible, synthetically useful and novel heterocyclic systems, for this reason. We focused our aim to use starting material possess a wide variety of potentially useful applications including biological, clinical and pharmacological areas. We found 4-aminoantipyrine (4AAP) possess the previously mentioned properties, so we used it as precursor to prepare polyfunctionally substituted heterocyclic compounds. The work divided into two parts, the first part discussed the utilization of N-(cyanoacetyl) aminoantipyrine for building new heterocyclic compounds. The second part discussed the formation of novel heterocyclic rings via the use of antipyrinylhydrazonomalononitrile as starting material. Both two parts followed by antimicrobial screening for the selected prepared compounds.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

The introduction part in this work presents a systematic and comprehensive survey of the methods of preparation and the chemical reactivity of cyanoacetamide derivatives. These compounds are important intermediates for the synthesis of a variety of otherwise difficulty accessible, synthetically useful and novel heterocyclic systems, for this reason. We focused our aim to use starting material possess a wide variety of potentially useful applications including biological, clinical and pharmacological areas. We found 4-aminoantipyrine (4AAP) possess the previously mentioned properties, so we used it as precursor to prepare polyfunctionally substituted heterocyclic compounds. The work divided into two parts, the first part discussed the utilization of N-(cyanoacetyl) aminoantipyrine for building new heterocyclic compounds. The second part discussed the formation of novel heterocyclic rings via the use of antipyrinylhydrazonomalononitrile as starting material. Both two parts followed by antimicrobial screening for the selected prepared compounds.

Biographie de l'auteur

Ramy Rabie has obtained his Master Degree in Organic Chemistry in 2008 Mansoura, Egypt. He has worked in different fields of Chemistry (Egyptian Armed Force-Chemical War 2003-05),(Instructor of Chemistry- Mansoura University 2005-08),(Chemist in the Central Lab.of Dakahlia Water Company 2003-10). In 2010 he joined the SEGAS Lab Staff until now.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2012
Langue
anglais
ISBN 10 
384848787X
ISBN 13 
9783848487875
Reliure
Broché
Nombre de pages
188
Coordonnées du fabricant
non disponible
Personne responsable
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