Articles liés à 1,3-Pyrimidine Derivatives: Synthesis and Antimicrobial...

1,3-Pyrimidine Derivatives: Synthesis and Antimicrobial Activity - Couverture souple

Pathak, Anoop Kumar; Chawla, Viney; Saraf, Shailendra K.

 
9783848488353: 1,3-Pyrimidine Derivatives: Synthesis and Antimicrobial Activity
Couverture souple
ISBN 10 : 3848488353 ISBN 13 : 9783848488353
Editeur : LAP LAMBERT Academic Publishing, 2012

Synopsis

There has been growing menace of antibiotic resistance in recent past owing to a number of reasons such as self medication and non-compliance on parts of patients with regard to complete dosage regimen. Medicinal chemists are hard pressed to bring about new molecules to cater to this need. 1,3-pyrimidine derivatives have been explored by a number of scientists worldwide and such these derivatives have emerged potential lead molecules for development of newer antimicrobial moieties. The present work reports the syntheses and evaluation of some 2-(6’-fluorobenzothiazol-2’-ylamino)-4,6-(disubstituted thiouriedo) -1,3-pyrimidine derivatives. Some of the synthesized derivatives showed excellent activity against Gram +ve bacteria Staphyllococcus aureus, Bacillus subtilis, and Gram -ve bacteria Escherichia coli and Pseudomonas aeruginosa. The contents of this book must make an excellent read for those interested in antibiotic research and allied interests.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

There has been growing menace of antibiotic resistance in recent past owing to a number of reasons such as self medication and non-compliance on parts of patients with regard to complete dosage regimen. Medicinal chemists are hard pressed to bring about new molecules to cater to this need. 1,3-pyrimidine derivatives have been explored by a number of scientists worldwide and such these derivatives have emerged potential lead molecules for development of newer antimicrobial moieties. The present work reports the syntheses and evaluation of some 2-(6’-fluorobenzothiazol-2’-ylamino)-4,6-(disubstituted thiouriedo) -1,3-pyrimidine derivatives. Some of the synthesized derivatives showed excellent activity against Gram +ve bacteria Staphyllococcus aureus, Bacillus subtilis, and Gram -ve bacteria Escherichia coli and Pseudomonas aeruginosa. The contents of this book must make an excellent read for those interested in antibiotic research and allied interests.

Biographie de l'auteur

Assistant Professor since four years at N.N.M. College of Pharmacy, Nawabganj, Gonda, India.Studied M. Pharm. at Faculty of Pharmacy, BBDNIIT, Lucknow, India. Has active interest in medicinal agents acting as antimicrobials. Has published research paper on 1, 3-pyrimidine derivatives as antimicrobial agents.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2012
Langue
anglais
ISBN 10 
3848488353
ISBN 13 
9783848488353
Reliure
Broché
Nombre de pages
116
Coordonnées du fabricant
non disponible
Personne responsable
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