Fenoprofen Calcium Compressed Coated Tablets for Colon Drug Delivery: Fenoprofen Calcium Compressed Coated Tablets - Couverture souple

Potu, Apparao; Shashidher, Burra; Pasunooti, Sandeep

Couverture souple

ISBN 10 : 3848497026 ISBN 13 : 9783848497027

Editeur : LAP LAMBERT Academic Publishing, 2012

A propos du livre

Présentation de l'éditeur

The aim of this study was to design and evaluate a colon targeting delivery for fenoprofen calcium with better benefits in treating the arthritis. Compression coated tablets were prepared by using guar gum as a coating material over core tablets. These systems would benefit for the high amount release of the drug in the distal intestinal or the colon, this may exhibit better fenoprofen calcium toward the arthritis by reduce the serious gastrointestinal (GI) adverse events including inflammation, bleeding, ulceration, and perforation of the stomach, small intestine or large intestine. Plan of work: 1) Formulation of fenoprofen calcium core tablets by direct compression. 2) Compression coating over the fenoprofen calcium core tablets using guar gum as a coating material. 3) Optimization of the coat thickness as the minimum that can provide protection against the gastric and intestinal environment. 4) Characterization of prepared powder mixer  Angle of repose  Bulk density  Tapped density  Carr’s index(compressibility index) 5) Characterization of core and compression coated tablets for following parameters  Weight variation  Tablet thickness  Tablet hardness  Friabil

Biographie de l'auteur

I Apparao Potu, Professor in Pharmacy, 24 years teaching experience, conducted several research and published in international journals, find out the manuscript and do needful.Thank you

Détails de l'édition

• Éditeur: LAP LAMBERT Academic Publishing
• Date d'édition: 2012
• Langue: anglais
• ISBN 10: 3848497026
• ISBN 13: 9783848497027
• Reliure: Broché
• Nombre de pages: 92
• Coordonnées du fabricant: non disponible
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