Modelling Atherosclerosis: Towards the Mathematical Prediction - Couverture souple

EL KHATIB, Nader

 
9786131527982: Modelling Atherosclerosis: Towards the Mathematical Prediction
Couverture souple
ISBN 10 : 6131527989 ISBN 13 : 9786131527982
Editeur : Éditions universitaires européennes, 2010

Synopsis

Atherosclerosis is an inflammatory disease which starts when low density lipoproteins (LDL) enter the intima of blood vessel where they are oxidized (ox-LDL). The ox-LDL is considered as a dangerous agent by the immune system provoking an anti-inflammatory response. This immune response triggers the recruitment of monocytes into the intima where they differentiate into macrophages and foam cells. The latter amplifies the production of inflammatory cytokines and further recruitment of monocytes. This auto-amplified process is compensated by the secretion of anti-inflammatory cytokines biochemical anti-inflammation) and triggers the migration of smooth muscle cells to form a fibrous cap that covers the lipid core. These fibrous caps with the lipid core are called atherosclerosis plaque. It changes the geometry of the blood vessel by narrowing it and interacts with the blood flow. This interaction may have dangerous consequences related to the plaque rupture or to the formation of blood clot. This book is devoted to mathematical modelling ofthese phenomena.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

Atherosclerosis is an inflammatory disease which starts when low density lipoproteins (LDL) enter the intima of blood vessel where they are oxidized (ox-LDL). The ox-LDL is considered as a dangerous agent by the immune system provoking an anti-inflammatory response. This immune response triggers the recruitment of monocytes into the intima where they differentiate into macrophages and foam cells. The latter amplifies the production of inflammatory cytokines and further recruitment of monocytes. This auto-amplified process is compensated by the secretion of anti-inflammatory cytokines biochemical anti-inflammation) and triggers the migration of smooth muscle cells to form a fibrous cap that covers the lipid core. These fibrous caps with the lipid core are called atherosclerosis plaque. It changes the geometry of the blood vessel by narrowing it and interacts with the blood flow. This interaction may have dangerous consequences related to the plaque rupture or to the formation of blood clot. This book is devoted to mathematical modelling ofthese phenomena.

Biographie de l'auteur

Nader El Khatib, PhD in applied mathematics, mathematical modelling and applications on biology and medicine,professor and researcher at the École Centrale de Lyon, France.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
Éditions universitaires européennes
Date d'édition
2010
Langue
anglais
ISBN 10 
6131527989
ISBN 13 
9786131527982
Reliure
Broché
Nombre de pages
96
Coordonnées du fabricant
non disponible
Personne responsable
Andreas Meier
22029659400
info@rheinberg-buch.de

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