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Synopsis
Expression patterns of microRNAs in body fluids can be used as non-invasive rapid and accurate biomarkers for various diseases. The study aimed to identify patterns of microRNA signatures for diagnosis of TB and assess significance of a patient’s genetic background on signature composition and diagnostic performance. The consented participant with; active tuberculosis, active TB co-infected with HIV, latent TB infection, other pulmonary infection and healthy individuals were enrolled from Italy and East Africa. A signature of 15 miRNAs was observe to differentiate healthy individuals from those with PTB with a diagnostic accuracy of 82% in the RVM and 77% in the logistic classification model. The analysis based on genetic background identified a signature of 10 miRNAs that was specific for the European with a diagnostic accuracy of 83% in RVM, and 81% in the logistic model. Whereas a signature of 12 miRNAs was specific to the African cohort and the diagnostic accuracy increased up to 95% and 100% in RVM and logistic model, respectively.miRNAs are a promising diagnostic candidate for TB, therefore further prospective evaluation of this diagnostic seems warranted to scientist.
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Serum microRNAs as Biomarker for Active and Latent TB Infection
Edité par
LAP LAMBERT Academic Publishing, 2018
ISBN 10 : 6138390288
ISBN 13 : 9786138390282
Neuf
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Vendeur : Books Puddle, New York, NY, Etats-Unis
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Etat : New. N° de réf. du vendeur 26389203508
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Serum microRNAs as Biomarker for Active and Latent TB Infection
Edité par
LAP LAMBERT Academic Publishing Apr 2018, 2018
ISBN 10 : 6138390288
ISBN 13 : 9786138390282
Neuf
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Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne
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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Expression patterns of microRNAs in body fluids can be used as non-invasive rapid and accurate biomarkers for various diseases. The study aimed to identify patterns of microRNA signatures for diagnosis of TB and assess significance of a patient's genetic background on signature composition and diagnostic performance. The consented participant with; active tuberculosis, active TB co-infected with HIV, latent TB infection, other pulmonary infection and healthy individuals were enrolled from Italy and East Africa. A signature of 15 miRNAs was observe to differentiate healthy individuals from those with PTB with a diagnostic accuracy of 82% in the RVM and 77% in the logistic classification model. The analysis based on genetic background identified a signature of 10 miRNAs that was specific for the European with a diagnostic accuracy of 83% in RVM, and 81% in the logistic model. Whereas a signature of 12 miRNAs was specific to the African cohort and the diagnostic accuracy increased up to 95% and 100% in RVM and logistic model, respectively.miRNAs are a promising diagnostic candidate for TB, therefore further prospective evaluation of this diagnostic seems warranted to scientist. 76 pp. Englisch. N° de réf. du vendeur 9786138390282
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Serum microRNAs as Biomarker for Active and Latent TB Infection
Edité par
LAP LAMBERT Academic Publishing, 2018
ISBN 10 : 6138390288
ISBN 13 : 9786138390282
Neuf
Couverture souple
Vendeur : Majestic Books, Hounslow, Royaume-Uni
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Etat : New. Print on Demand. N° de réf. du vendeur 390429163
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Serum microRNAs as Biomarker for Active and Latent TB Infection
Edité par
LAP LAMBERT Academic Publishing, 2018
ISBN 10 : 6138390288
ISBN 13 : 9786138390282
Neuf
Couverture souple
Vendeur : Biblios, Frankfurt am main, HESSE, Allemagne
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Serum microRNAs as Biomarker for Active and Latent TB Infection
Edité par
LAP LAMBERT Academic Publishing, 2018
ISBN 10 : 6138390288
ISBN 13 : 9786138390282
Neuf
Couverture souple
Vendeur : moluna, Greven, Allemagne
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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Mwangoka Grace WynnGrace W Mwangoka PhD, studied at Ludwig Maximilians University. Senior scientist at Ifakara Health Institute. I worked in evaluation of safety and efficacy of malaria vaccine and drugs. With other partners we asses. N° de réf. du vendeur 507124951
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Serum microRNAs as Biomarker for Active and Latent TB Infection
Edité par
LAP LAMBERT Academic Publishing Apr 2018, 2018
ISBN 10 : 6138390288
ISBN 13 : 9786138390282
Neuf
Taschenbuch
Vendeur : buchversandmimpf2000, Emtmannsberg, BAYE, Allemagne
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Taschenbuch. Etat : Neu. Neuware -Expression patterns of microRNAs in body fluids can be used as non-invasive rapid and accurate biomarkers for various diseases. The study aimed to identify patterns of microRNA signatures for diagnosis of TB and assess significance of a patient¿s genetic background on signature composition and diagnostic performance. The consented participant with; active tuberculosis, active TB co-infected with HIV, latent TB infection, other pulmonary infection and healthy individuals were enrolled from Italy and East Africa. A signature of 15 miRNAs was observe to differentiate healthy individuals from those with PTB with a diagnostic accuracy of 82% in the RVM and 77% in the logistic classification model. The analysis based on genetic background identified a signature of 10 miRNAs that was specific for the European with a diagnostic accuracy of 83% in RVM, and 81% in the logistic model. Whereas a signature of 12 miRNAs was specific to the African cohort and the diagnostic accuracy increased up to 95% and 100% in RVM and logistic model, respectively.miRNAs are a promising diagnostic candidate for TB, therefore further prospective evaluation of this diagnostic seems warranted to scientist.Books on Demand GmbH, Überseering 33, 22297 Hamburg 76 pp. Englisch. N° de réf. du vendeur 9786138390282
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Serum microRNAs as Biomarker for Active and Latent TB Infection
Edité par
LAP LAMBERT Academic Publishing, 2018
ISBN 10 : 6138390288
ISBN 13 : 9786138390282
Neuf
Taschenbuch
Vendeur : AHA-BUCH GmbH, Einbeck, Allemagne
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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Expression patterns of microRNAs in body fluids can be used as non-invasive rapid and accurate biomarkers for various diseases. The study aimed to identify patterns of microRNA signatures for diagnosis of TB and assess significance of a patient's genetic background on signature composition and diagnostic performance. The consented participant with; active tuberculosis, active TB co-infected with HIV, latent TB infection, other pulmonary infection and healthy individuals were enrolled from Italy and East Africa. A signature of 15 miRNAs was observe to differentiate healthy individuals from those with PTB with a diagnostic accuracy of 82% in the RVM and 77% in the logistic classification model. The analysis based on genetic background identified a signature of 10 miRNAs that was specific for the European with a diagnostic accuracy of 83% in RVM, and 81% in the logistic model. Whereas a signature of 12 miRNAs was specific to the African cohort and the diagnostic accuracy increased up to 95% and 100% in RVM and logistic model, respectively.miRNAs are a promising diagnostic candidate for TB, therefore further prospective evaluation of this diagnostic seems warranted to scientist. N° de réf. du vendeur 9786138390282
Quantité disponible : 1 disponible(s)