Articles liés à Preparation and Characterization of Co-crystal: to...

Preparation and Characterization of Co-crystal: to improve the physicochemical properties drug - Couverture souple

Patond, Vishal; Thenge, Raju; Narkhede, Mahesh

 
9786138926559: Preparation and Characterization of Co-crystal: to improve the physicochemical properties drug

Synopsis

A co-crystal might be the expected outcome of a co crystallization experiment in which the final crystal contains at least two distinct species connected by intermolecular forces. Pharmaceutical co-crystals draw closer the fields of crystal engineering and pharmaceutical sciences. A pharmaceutical co-crystal is a single crystalline solid that incorporates two neutral molecules, one being an API and other a co-crystal former The basic physiochemical properties of co-crystal can usually be characterized by : A. Fourier transport Infrared spectroscopy [FTIR] ; B. Differential scanning calorimetry [DSC] ; C. X-ray diffraction [XRD].

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