Formulation, Design and Characterization of Mucoadhesive Buccal Film: Buccal Film - Couverture souple

Shinde, Anilkumar ; More, Harinath

9786139848171: Formulation, Design and Characterization of Mucoadhesive Buccal Film: Buccal Film

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ISBN 10 : 6139848172 ISBN 13 : 9786139848171

Editeur : LAP LAMBERT Academic Publishing, 2018

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�diteur: LAP LAMBERT Academic Publishing
Date d'�dition: 2018
Langue: anglais
ISBN 10: 6139848172
ISBN 13: 9786139848171
Reliure: Broch�
Nombre de pages: 64
Coordonn�es du fabricant: non disponible
Personne responsable: non disponible

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Formulation, Design and Characterization of Mucoadhesive Buccal Film

Anilkumar Shinde

Edit� par LAP LAMBERT Academic Publishing Mai 2018, 2018

ISBN 10 : 6139848172 ISBN 13 : 9786139848171

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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The present investigation was to formulation and development of fast dissolving mucoadhesive buccal film of nebivolol by using solvent casting method. Nebivolol is a third-generation cardio selective beta1-blocker undergoes extensive metabolism in the liver, gastrointestinal disturbance, abdominal pain after its oral administration and resulting in to a poor bioavailability (10-12%). In order to improve the bioavailability, efficacy and minimize the side effects associated with oral administration. Prepared mucoadhesive buccal films using HPMC E15 and PVP as mucoadhesive polymers. Among the two polymers HPMC E15 showed an increased in-vitro residence time due to high mucoadhesive property. Mucoadhesive buccal films were evaluated by weight variation, thickness, folding endurance, pH, in vitro disintegration, in vitro dissolution, tensile strength and drug content. In-vitro drug release study was showed more than 98.19�0.02% drug released within 40 min. The tensile strength of formulation SW9 was found 50.00 N/mm2. Thus it can concluded that the prepared formulation of buccal mucoadhesive film can be a novel treatment for myocardial infarction and angina pectoris. 64 pp. Englisch. N� de r�f. du vendeur 9786139848171

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Formulation, Design and Characterization of Mucoadhesive Buccal Film

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ISBN 10 : 6139848172 ISBN 13 : 9786139848171

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Formulation, Design and Characterization of Mucoadhesive Buccal Film

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Formulation, Design and Characterization of Mucoadhesive Buccal Film

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ISBN 10 : 6139848172 ISBN 13 : 9786139848171

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Formulation, Design and Characterization of Mucoadhesive Buccal Film

Anilkumar Shinde|Harinath More

Edit� par LAP LAMBERT Academic Publishing, 2018

ISBN 10 : 6139848172 ISBN 13 : 9786139848171

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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Shinde AnilkumarDr. Anilkumar j Shinde M.Pharm Ph.D started his career in Pune university as Lecturer in Pharmaceutics & younged in teaching since 1994. Presently he is working as Associate Professor in Pharmaceutics Department. He i. N� de r�f. du vendeur 385661865

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Formulation, Design and Characterization of Mucoadhesive Buccal Film

Anilkumar Shinde

Edit� par LAP LAMBERT Academic Publishing Mai 2018, 2018

ISBN 10 : 6139848172 ISBN 13 : 9786139848171

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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -The present investigation was to formulation and development of fast dissolving mucoadhesive buccal film of nebivolol by using solvent casting method. Nebivolol is a third-generation cardio selective �1-blocker undergoes extensive metabolism in the liver, gastrointestinal disturbance, abdominal pain after its oral administration and resulting in to a poor bioavailability (10-12%). In order to improve the bioavailability, efficacy and minimize the side effects associated with oral administration. Prepared mucoadhesive buccal films using HPMC E15 and PVP as mucoadhesive polymers. Among the two polymers HPMC E15 showed an increased in-vitro residence time due to high mucoadhesive property. Mucoadhesive buccal films were evaluated by weight variation, thickness, folding endurance, pH, in vitro disintegration, in vitro dissolution, tensile strength and drug content. In-vitro drug release study was showed more than 98.19�0.02% drug released within 40 min. The tensile strength of formulation SW9 was found 50.00 N/mm2. Thus it can concluded that the prepared formulation of buccal mucoadhesive film can be a novel treatment for myocardial infarction and angina pectoris.VDM Verlag, Dudweiler Landstra�e 99, 66123 Saarbr�cken 64 pp. Englisch. N� de r�f. du vendeur 9786139848171

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Formulation, Design and Characterization of Mucoadhesive Buccal Film : Buccal Film

Anilkumar Shinde

Edit� par LAP LAMBERT Academic Publishing

ISBN 10 : 6139848172 ISBN 13 : 9786139848171

Neuf Taschenbuch

impression � la demande

Vendeur : AHA-BUCH GmbH, Einbeck, Allemagne

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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The present investigation was to formulation and development of fast dissolving mucoadhesive buccal film of nebivolol by using solvent casting method. Nebivolol is a third-generation cardio selective beta1-blocker undergoes extensive metabolism in the liver, gastrointestinal disturbance, abdominal pain after its oral administration and resulting in to a poor bioavailability (10-12%). In order to improve the bioavailability, efficacy and minimize the side effects associated with oral administration. Prepared mucoadhesive buccal films using HPMC E15 and PVP as mucoadhesive polymers. Among the two polymers HPMC E15 showed an increased in-vitro residence time due to high mucoadhesive property. Mucoadhesive buccal films were evaluated by weight variation, thickness, folding endurance, pH, in vitro disintegration, in vitro dissolution, tensile strength and drug content. In-vitro drug release study was showed more than 98.19�0.02% drug released within 40 min. The tensile strength of formulation SW9 was found 50.00 N/mm2. Thus it can concluded that the prepared formulation of buccal mucoadhesive film can be a novel treatment for myocardial infarction and angina pectoris. N� de r�f. du vendeur 9786139848171

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