Mesenchymal Stem Cell-based Differentiation of Smooth Muscle Cells - Couverture souple

Fonseca Amaral, Luis Manuel

 
9786139902774: Mesenchymal Stem Cell-based Differentiation of Smooth Muscle Cells
Couverture souple
ISBN 10 : 6139902770 ISBN 13 : 9786139902774
Editeur : LAP LAMBERT Academic Publishing, 2019

Synopsis

Valvular heart disease is a major health and socioeconomic problem worldwide with approximately 300 000 valve replacements performed annually. Tissue-engineered heart valves with repair and remodelling capabilities could overcome the limitations of today’s valvular prostheses. One major limitation to this approach has been finding a reliable source of smooth muscle cells (SMC) because biopsies of these cells can be impractical and morbid as also present limited replicative capacity. The ideal cell source should be harvested in a non-or minimally invasive way and should deliver an initial high number of cells in order to drastically reduce the time needed for cell expansion. For these reasons there are many studies endeavoured to explore whether functional SMC could be generated from various types of adult mesenchymal stem cells (MSC): Umbilical cord (UC-MSC), bone marrow (BM-MSC), adipose derived (AD-MSC) and chorionic villi (CV-MSC) as possible sources for heart valve therapy. The MSC from different sources were isolated and expanded of healthy and different donor.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2019
Langue
anglais
ISBN 10 
6139902770
ISBN 13 
9786139902774
Reliure
Broché
Nombre de pages
124
Coordonnées du fabricant
non disponible
Personne responsable
KreGa Onlinehandel GmbH
4950000000000
info@krega-onlinehandel.de

Birkenweg 31
Brakel
33034
Allemagne