Formulation of Film Coated Tablets of Norfloxacin and Tinidazole - Couverture souple

Shinde, Anilkumar; More, Harinath

 
9786139977369: Formulation of Film Coated Tablets of Norfloxacin and Tinidazole
Couverture souple
ISBN 10 : 6139977363 ISBN 13 : 9786139977369
Editeur : LAP Lambert Academic Publishing, 2018

Synopsis

The aim of the present study was development and optimization of an efficacious, pharmaco-economical, palatable and marketable film coated tablet formulation of Norfloxacin-Tinidazole. Bitter taste of both drugs reduces the patient compliance & hence marketability. However it has been shown that film coating technology economical & useful in masking the taste. The core tablets with maximum hardness & minimum disintegration time were selected for film coating. (F-1 & F-07) The optimized formulation F-07 showed hardness, friability, disintegration time and drug release in range 9 kg/cm2, 0.17±0.02%, 27.40±2.1 sec. & 100% release in 30 min. respectively. For all tablet formulation drug release at the end of 30 min was found in the range of 52.78±0.09 to 100.07±0.5 % and from the obtained results, F-07 was selected as an optimized formulation for designing palatable tablet. Therefore it can be concluded that the present work discusses in depth the development and optimization of an efficacious, pharmaco-economical, palatable and marketable tablet formulation of Norfloxacin and Tinidazole.

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Éditeur
LAP Lambert Academic Publishing
Date d'édition
2018
Langue
anglais
ISBN 10 
6139977363
ISBN 13 
9786139977369
Reliure
Broché
Nombre de pages
96
Coordonnées du fabricant
non disponible
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