A facile synthesis of pyrazole based 1,2,4,5-tetrazino[1,6-a]quinoline derivatives 11a-o have been synthesized through the reaction of compounds 9a-c and substituted hydrazines 10a-e in presence of conc. H2SO4 as a solvent under reflux at 80° for 3-4.5 hr. The reaction proceeded efficiently to get the desire product in excellent yields (74-86%). The structures of the title compounds were confirmed by FT-IR, 1H NMR, 13C NMR and mass spectrometry. The newly synthesized compounds were screened for their preliminary in vitro antibacterial activity against a panel of pathogenic strains of bacteria and fungi, antituberculosis activity against Mycobacterium tuberculosis H37Rv and antimalarial activity against Plasmodium falciparum. Most of them exhibited significant antibacterial activity as compared to the first line drugs. This work is useful for the research students and academia educations.
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Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne
Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A facile synthesis of pyrazole based 1,2,4,5-tetrazino[1,6-a]quinoline derivatives 11a-o have been synthesized through the reaction of compounds 9a-c and substituted hydrazines 10a-e in presence of conc. H2SO4 as a solvent under reflux at 80° for 3-4.5 hr. The reaction proceeded efficiently to get the desire product in excellent yields (74-86%). The structures of the title compounds were confirmed by FT-IR, 1H NMR, 13C NMR and mass spectrometry. The newly synthesized compounds were screened for their preliminary in vitro antibacterial activity against a panel of pathogenic strains of bacteria and fungi, antituberculosis activity against Mycobacterium tuberculosis H37Rv and antimalarial activity against Plasmodium falciparum. Most of them exhibited significant antibacterial activity as compared to the first line drugs. This work is useful for the research students and academia educations. 52 pp. Englisch. N° de réf. du vendeur 9786200286819
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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Patel Haresh B.Dr. Haresh B Patel did his M.Sc. with specialization of analytical chemistry and his PhD under the guidance of Dr. Manish P. Patel sir from Sardar Patel University Vallabh Vidyanagar. His research area is synthesis, ch. N° de réf. du vendeur 385887315
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Vendeur : Revaluation Books, Exeter, Royaume-Uni
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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -A facile synthesis of pyrazole based 1,2,4,5-tetrazino[1,6-a]quinoline derivatives 11a-o have been synthesized through the reaction of compounds 9a-c and substituted hydrazines 10a-e in presence of conc. H2SO4 as a solvent under reflux at 80° for 3-4.5 hr. The reaction proceeded efficiently to get the desire product in excellent yields (74-86%). The structures of the title compounds were confirmed by FT-IR, 1H NMR, 13C NMR and mass spectrometry. The newly synthesized compounds were screened for their preliminary in vitro antibacterial activity against a panel of pathogenic strains of bacteria and fungi, antituberculosis activity against Mycobacterium tuberculosis H37Rv and antimalarial activity against Plasmodium falciparum. Most of them exhibited significant antibacterial activity as compared to the first line drugs. This work is useful for the research students and academia educations.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 52 pp. Englisch. N° de réf. du vendeur 9786200286819
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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - A facile synthesis of pyrazole based 1,2,4,5-tetrazino[1,6-a]quinoline derivatives 11a-o have been synthesized through the reaction of compounds 9a-c and substituted hydrazines 10a-e in presence of conc. H2SO4 as a solvent under reflux at 80° for 3-4.5 hr. The reaction proceeded efficiently to get the desire product in excellent yields (74-86%). The structures of the title compounds were confirmed by FT-IR, 1H NMR, 13C NMR and mass spectrometry. The newly synthesized compounds were screened for their preliminary in vitro antibacterial activity against a panel of pathogenic strains of bacteria and fungi, antituberculosis activity against Mycobacterium tuberculosis H37Rv and antimalarial activity against Plasmodium falciparum. Most of them exhibited significant antibacterial activity as compared to the first line drugs. This work is useful for the research students and academia educations. N° de réf. du vendeur 9786200286819
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Vendeur : preigu, Osnabrück, Allemagne
Taschenbuch. Etat : Neu. Synthesis, Characterization and Biological Evaluation of Heterocycles | Synthesis, Characterization and Biological Screening of pyrazole based 1,2,4,5-tetrazino[1,6-a]quinoline derivatives | Haresh B. Patel (u. a.) | Taschenbuch | 52 S. | Englisch | 2019 | LAP LAMBERT Academic Publishing | EAN 9786200286819 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. N° de réf. du vendeur 117395323
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Vendeur : Mispah books, Redhill, SURRE, Royaume-Uni
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