NANOPARTICLES WITH THE AGGREGATION-INDUCED EMISSION EFFECT: PROPERTIES AND APPLICATIONS: Photosensitizers for Photodynamic Therapy - Couverture souple

Korotkova, Irina; Sakhno, Tamara

 
9786200499141: NANOPARTICLES WITH THE AGGREGATION-INDUCED EMISSION EFFECT: PROPERTIES AND APPLICATIONS: Photosensitizers for Photodynamic Therapy
Couverture souple
ISBN 10 : 6200499144 ISBN 13 : 9786200499141
Editeur : LAP LAMBERT Academic Publishing, 2020

Synopsis

Photodynamic therapy (PDT) is a method of the treatment of localized cancers, based on a photochemical reaction between a light-activated molecule or photosensitizer (PS), light, and molecular oxygen. Correct choice of PS is of fundamental importance for PDT efficacy. Despite numerous studies in this field, most known PS have some drawbacks, e.g. lack of specificity and aggregation in aqueous media. Consequently, the search for an ideal PS is essential for further development of PDT. Here we review classification and analyze main featuresof different generations of PS and describe the mechanisms of their action. Various methods of targeted delivery of PS to tumor cells are discussed. The advantages of PS nanoparticles with the effect of aggregation-induced emission (AIE) over the classic photosensitizers are presented. A possibility of practical application of such light-emitting structures in cancer phototherapy is shown.

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Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2020
Langue
anglais
ISBN 10 
6200499144
ISBN 13 
9786200499141
Reliure
Broché
Nombre de pages
92
Coordonnées du fabricant
Buchpark GmbH
https://www.buchpark.de

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