Formulation & Development of Lamotrigine Orodispersible Tablet: Liquisolid Technology - Couverture souple
Synopsis
Lamotrigine comes under the category of anti-epileptic drug. It is a BCS class II drug which is insoluble in water and its half-life is 24-25 hours with 90% bioavailability. To obtain an enhanced in-vitro dissolution rate of Lamotrigine by using Liquisolid technique and Liquisolid tablets were optimized by QbD-DoE approach 32 full factorial design using Design Expert Software. All prepared liquisolid batches were subjected to weight variation, drug content uniformity, hardness, friability test, and disintegration test and dissolution tests. Liquisolid systems were also tested for DSC, FT-IR. From result of check point analysis of design data, LMLCODT1 shows higher Drug release at LAMOTRIGINE less wetting time and disintegrating time (5.24 sec) which enhancing solubility of Lamotrigine by 4.73 mg/ml. Hence, this research work may be useful to formulate Orodispersible Tablets using Liquisolid Technique which may give rapid onset of action by rapid absorption, maximize efficacy, reduce dose and dose frequency & hence increase patient Compliance.
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Formulation & Development of Lamotrigine Orodispersible Tablet
Edité par
LAP LAMBERT Academic Publishing Mrz 2022, 2022
ISBN 10 : 6202028262
ISBN 13 : 9786202028264
Neuf
Taschenbuch
Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Lamotrigine comes under the category of anti-epileptic drug. It is a BCS class II drug which is insoluble in water and its half-life is 24-25 hours with 90% bioavailability. To obtain an enhanced in-vitro dissolution rate of Lamotrigine by using Liquisolid technique and Liquisolid tablets were optimized by QbD-DoE approach 32 full factorial design using Design Expert Software. All prepared liquisolid batches were subjected to weight variation, drug content uniformity, hardness, friability test, and disintegration test and dissolution tests. Liquisolid systems were also tested for DSC, FT-IR. From result of check point analysis of design data, LMLCODT1 shows higher Drug release at LAMOTRIGINE less wetting time and disintegrating time (5.24 sec) which enhancing solubility of Lamotrigine by 4.73 mg/ml. Hence, this research work may be useful to formulate Orodispersible Tablets using Liquisolid Technique which may give rapid onset of action by rapid absorption, maximize efficacy, reduce dose and dose frequency & hence increase patient Compliance. 164 pp. Englisch. N° de réf. du vendeur 9786202028264
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Formulation & Development of Lamotrigine Orodispersible Tablet
Edité par
LAP LAMBERT Academic Publishing, 2022
ISBN 10 : 6202028262
ISBN 13 : 9786202028264
Neuf
Couverture souple
Vendeur : moluna, Greven, Allemagne
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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Shah RumitDr. Rumit M. Shah is working as Associate Professor at Shree Naranajibhai Lalbhai Patel College of Pharmacy, Bardoli, Surat Gujarat, since 2009. He has published many national and international papers and actively participa. N° de réf. du vendeur 579533098
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Formulation & Development of Lamotrigine Orodispersible Tablet | Liquisolid Technology
Edité par
LAP LAMBERT Academic Publishing, 2022
ISBN 10 : 6202028262
ISBN 13 : 9786202028264
Neuf
Taschenbuch
Vendeur : preigu, Osnabrück, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Taschenbuch. Etat : Neu. Formulation & Development of Lamotrigine Orodispersible Tablet | Liquisolid Technology | Rumit Shah (u. a.) | Taschenbuch | Englisch | 2022 | LAP LAMBERT Academic Publishing | EAN 9786202028264 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. N° de réf. du vendeur 121407572
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Formulation & Development of Lamotrigine Orodispersible Tablet
Edité par
LAP LAMBERT Academic Publishing Mär 2022, 2022
ISBN 10 : 6202028262
ISBN 13 : 9786202028264
Neuf
Taschenbuch
Vendeur : buchversandmimpf2000, Emtmannsberg, BAYE, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Lamotrigine comes under the category of anti-epileptic drug. It is a BCS class II drug which is insoluble in water and its half-life is 24-25 hours with 90% bioavailability. To obtain an enhanced in-vitro dissolution rate of Lamotrigine by using Liquisolid technique and Liquisolid tablets were optimized by QbD-DoE approach 32 full factorial design using Design Expert Software. All prepared liquisolid batches were subjected to weight variation, drug content uniformity, hardness, friability test, and disintegration test and dissolution tests. Liquisolid systems were also tested for DSC, FT-IR. From result of check point analysis of design data, LMLCODT1 shows higher Drug release at LAMOTRIGINE less wetting time and disintegrating time (5.24 sec) which enhancing solubility of Lamotrigine by 4.73 mg/ml. Hence, this research work may be useful to formulate Orodispersible Tablets using Liquisolid Technique which may give rapid onset of action by rapid absorption, maximize efficacy, reduce dose and dose frequency & hence increase patient Compliance.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 164 pp. Englisch. N° de réf. du vendeur 9786202028264
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Formulation & Development of Lamotrigine Orodispersible Tablet : Liquisolid Technology
Edité par
LAP LAMBERT Academic Publishing, 2022
ISBN 10 : 6202028262
ISBN 13 : 9786202028264
Neuf
Taschenbuch
Vendeur : AHA-BUCH GmbH, Einbeck, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Lamotrigine comes under the category of anti-epileptic drug. It is a BCS class II drug which is insoluble in water and its half-life is 24-25 hours with 90% bioavailability. To obtain an enhanced in-vitro dissolution rate of Lamotrigine by using Liquisolid technique and Liquisolid tablets were optimized by QbD-DoE approach 32 full factorial design using Design Expert Software. All prepared liquisolid batches were subjected to weight variation, drug content uniformity, hardness, friability test, and disintegration test and dissolution tests. Liquisolid systems were also tested for DSC, FT-IR. From result of check point analysis of design data, LMLCODT1 shows higher Drug release at LAMOTRIGINE less wetting time and disintegrating time (5.24 sec) which enhancing solubility of Lamotrigine by 4.73 mg/ml. Hence, this research work may be useful to formulate Orodispersible Tablets using Liquisolid Technique which may give rapid onset of action by rapid absorption, maximize efficacy, reduce dose and dose frequency & hence increase patient Compliance. N° de réf. du vendeur 9786202028264
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EUR 80,86
Expédition à EUR 61,31
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