Articles liés à Multifunctional materials for modulating enzyme activities...

Multifunctional materials for modulating enzyme activities in wounds - Couverture souple

Francesko, Antonio

 
9786202050920: Multifunctional materials for modulating enzyme activities in wounds
Couverture souple
ISBN 10 : 6202050926 ISBN 13 : 9786202050920
Editeur : LAP LAMBERT Academic Publishing, 2017

Synopsis

This book is a result of various trials for development of active multifunctional dressing materials and nanoparticle formulations with suitable exploitation characteristics for chronic wounds treatment. The main focus is on biopolymer-based materials functionalised with active agents for controlled inhibition of major chronic wound enzymes. The capacity of these materials to inhibit proteolytic and oxidative enzymes involved in chronic inflammation was evaluated in vitro. Fabrication of sponge-like biopolymer dressings is described together with their impregnation with natural polyphenolic compounds to be released aiming at control of the deleterious wound enzyme activities. The exploitation characteristics of the sponges, i.e. mechanical properties, biostability, biocompatibility, extent and duration of wound enzymes inhibition, were evaluated. In another approach, thiolated biopolymers were processed into functional nanomaterials, namely: nanoscale films/coatings by using a layer-by-layer technology and nanoparticle formulations obtained from thiolated biopolymers in a one-step sonochemical process.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

This book is a result of various trials for development of active multifunctional dressing materials and nanoparticle formulations with suitable exploitation characteristics for chronic wounds treatment. The main focus is on biopolymer-based materials functionalised with active agents for controlled inhibition of major chronic wound enzymes. The capacity of these materials to inhibit proteolytic and oxidative enzymes involved in chronic inflammation was evaluated in vitro. Fabrication of sponge-like biopolymer dressings is described together with their impregnation with natural polyphenolic compounds to be released aiming at control of the deleterious wound enzyme activities. The exploitation characteristics of the sponges, i.e. mechanical properties, biostability, biocompatibility, extent and duration of wound enzymes inhibition, were evaluated. In another approach, thiolated biopolymers were processed into functional nanomaterials, namely: nanoscale films/coatings by using a layer-by-layer technology and nanoparticle formulations obtained from thiolated biopolymers in a one-step sonochemical process.

Biographie de l'auteur

Dr. Antonio Francesko earned a BSc in Biochemistry from the Belgrade University in 2006. In 2009 and 2012 Antonio received a MSc and a PhD in Polymers and Biopolymers Engineering from the Universitat Politècnica de Catalunya. He is currently a Senior Scientist at the University of Minho with research interests in applied nanobiotechnology.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2017
Langue
anglais
ISBN 10 
6202050926
ISBN 13 
9786202050920
Reliure
Broché
Nombre de pages
156
Coordonnées du fabricant
non disponible
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