Articles liés à SLNs and NLCs: Preparation, Characterization, Hurdles,...

SLNs and NLCs: Preparation, Characterization, Hurdles, and Strategies - Couverture souple

Poovi, Ganesan; Dhamodharan, Narayanasamy

 
9786202055420: SLNs and NLCs: Preparation, Characterization, Hurdles, and Strategies
Couverture souple
ISBN 10 : 6202055421 ISBN 13 : 9786202055420
Editeur : LAP LAMBERT Academic Publishing, 2017

Synopsis

The use of lipid particles in pharmaceutical technology has been reported for several years. Because the physicochemical diversity and biocompatibility of lipids and their ability to enhance oral bioavailability of drugs have made lipid nanoparticles very attractive carriers for oral drug delivery. The lipid nanoparticles with a solid matrix are two types: solid lipid nanoparticle (SLN) and nanostructured lipid carrier (NLC). Also, their hydrophobic core provides a suitable environment for entrapment of hydrophobic drugs to improve the bioavailability of the poorly water-soluble drug. This review highlights and discuss the types of simple and easily scaled-up novel lipid nanoparticles with solid matrix (SLN and NLC)) along with their different production techniques, hurdles and strategies for the production of lipid nanoparticles, characterization, lyophilization and drug release. Also, this review summarizes the research findings reported by the different researchers regarding the different method of preparation, excipients and their significant findings.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

The use of lipid particles in pharmaceutical technology has been reported for several years. Because the physicochemical diversity and biocompatibility of lipids and their ability to enhance oral bioavailability of drugs have made lipid nanoparticles very attractive carriers for oral drug delivery. The lipid nanoparticles with a solid matrix are two types: solid lipid nanoparticle (SLN) and nanostructured lipid carrier (NLC). Also, their hydrophobic core provides a suitable environment for entrapment of hydrophobic drugs to improve the bioavailability of the poorly water-soluble drug. This review highlights and discuss the types of simple and easily scaled-up novel lipid nanoparticles with solid matrix (SLN and NLC)) along with their different production techniques, hurdles and strategies for the production of lipid nanoparticles, characterization, lyophilization and drug release. Also, this review summarizes the research findings reported by the different researchers regarding the different method of preparation, excipients and their significant findings.

Biographie de l'auteur

Mrs. G. Poovi is an Asst. Professor of Pharmaceutics at College of Pharmacy, MTPG & RIHS, Puducherry and currently she is doing Ph. D under the guidance of Dr. N. Damodharan in the area of Lipid nanoparticles at College of Pharmacy, SRM University, Chennai, India. She served as the recruit committee member of VCRC, ICMR, Govt. of India. Puducherry.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2017
Langue
anglais
ISBN 10 
6202055421
ISBN 13 
9786202055420
Reliure
Broché
Nombre de pages
68
Coordonnées du fabricant
non disponible
Personne responsable
KreGa Onlinehandel GmbH
4950000000000
info@krega-onlinehandel.de

Birkenweg 31
Brakel
33034
Allemagne