Synthesis, Formulation and Evaluation of Some Selected Microspheres - Couverture souple

Engla, Gajanand; Soni, Love Kumar; Dixit, Vinod Kumar

Couverture souple

ISBN 10 : 6202079002 ISBN 13 : 9786202079006

Editeur : LAP LAMBERT Academic Publishing, 2017

Synopsis

Excellent achievements have been made in management/treatment of disease conditions through invention of newer drug entities or therapies over the past two decades. Diabetes is growing in today’s world at a very high speed and indeed Oral Hypoglycaemic agents are one of the major breakthroughs in this context. But because of short plasma half life & repetitive dosing, this treatment becomes inconvenient and problematic. In the present work, efforts were made to design a biodegradable micro-particulate drug delivery system which promises in maintaining the plasma drug level without repetitive dosing. The primary objective of the present research work was to prepare a long circulating drug delivery system of oral hypoglycaemic drugs for long term management of Type-II diabetes mellitus with improved efficacy by microsphere for overcoming the problems of drug delivery through conventional dosage forms. The proposed micro-particulate drug delivery system of biodegradable polymers was capable to maintain the blood sugar level for few days, without the need for frequent dosing; decreased side effects as in case of conventional drug delivery and hence increased patient compliance.

Détails de l'édition

• Éditeur: LAP LAMBERT Academic Publishing
• Date d'édition: 2017
• Langue: anglais
• ISBN 10: 6202079002
• ISBN 13: 9786202079006
• Reliure: Broché
• Nombre de pages: 332
• Coordonnées du fabricant: non disponible
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