Expression of p53 in Prostate Cancer Patients - Couverture souple

Arif, Maria; Arif, Taha; Omer, Aadil

 
9786202313049: Expression of p53 in Prostate Cancer Patients
Couverture souple
ISBN 10 : 6202313048 ISBN 13 : 9786202313049
Editeur : Scholars' Press, 2018

Synopsis

Prostate cancer (CaP) is most commonly diagnosed non-dermatological solid malignancy with a high metastatic rate. The growing prevalence of cancer survivors was estimated to be over 28 million worldwide. CaP is the second most common cancer in males of USA and high incidence has been reported in United Kingdom, African, Brazilian and Pakistani men. p53 has an important role in CaP. It plays an critical role in cancer metastasis. The tumor suppressor gene, p53, was found to be at the center of hub of significant biological pathways Reactive oxygen species (ROS) could activate some specific signaling pathways that contribute to tumor development by regulating cell proliferation, angiogenesis and metastasis processes. Current study was designed to determine expression of p53 in CaP as compared to normal control. This is a Cross-sectional analytical study which was conducted at Department of Biochemistry & Molecular Biology & Department of Urology, Rawalpindi, National University of Science and Technology, Islamabad over a period of one year. Study included 32 samples. Expression of p53 was determined by real time qPCR. It has been seen that CaP is an age related disease. Optimum ann

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Éditeur
Scholars' Press
Date d'édition
2018
Langue
anglais
ISBN 10 
6202313048
ISBN 13 
9786202313049
Reliure
Broché
Nombre de pages
60
Coordonnées du fabricant
non disponible
Personne responsable
non disponible