DEVELOPMENT OF LORNXICAM MICROSPONGES GEL FOR TOPICAL APPLICATION: LORNXICAM MICROSPONGES GEL - Couverture souple

Shinde, Anilkumar ; More, Harinath

9786202519199: DEVELOPMENT OF LORNXICAM MICROSPONGES GEL FOR TOPICAL APPLICATION: LORNXICAM MICROSPONGES GEL

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ISBN 10 : 6202519193 ISBN 13 : 9786202519199

Editeur : LAP LAMBERT Academic Publishing, 2020

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The aim of the present study was to prepare microsponges gel formulation containing lornixicam by quasi emulsion solvent diffusion method. Lornoxicam is a Non-steroidal anti-inflammatory drug used for the treatment of various inflammatory diseases. Microsponges were spherical, uniform in shape, between 19 to 136μm in diameter. The production yield, actual drug content and encapsulation efficiency was found in the range of 57.14�0.47 to 88.57�0.799%, 54.78�0.76 to 83.55�0.65%, and 65.73�0.35 % to 95.04�0.42 respectively. The results of compatibility studies FTIR, PXRD, DSC and accelerated stability studies showed that no chemical interaction with drug and excipients. The dermal observation of skin irritation study shows no sign of either erythema or edema after 24 hrs of application. In % inhibition was more in microsponges gel as compare with pure drug gel in anti- inflammatory activity. Formulation of lornoxicam microsponges provides better control over release of drug. This study presents a new approach based on microsponge drug delivery system for topical application.

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�diteur: LAP LAMBERT Academic Publishing
Date d'�dition: 2020
Langue: anglais
ISBN 10: 6202519193
ISBN 13: 9786202519199
Reliure: Broch�
Nombre de pages: 108
Coordonn�es du fabricant: non disponible
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DEVELOPMENT OF LORNXICAM MICROSPONGES GEL FOR TOPICAL APPLICATION

Anilkumar Shinde

Edit� par LAP LAMBERT Academic Publishing Apr 2020, 2020

ISBN 10 : 6202519193 ISBN 13 : 9786202519199

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Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne

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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The aim of the present study was to prepare microsponges gel formulation containing lornixicam by quasi emulsion solvent diffusion method. Lornoxicam is a Non-steroidal anti-inflammatory drug used for the treatment of various inflammatory diseases. Microsponges were spherical, uniform in shape, between 19 to 136mim in diameter. The production yield, actual drug content and encapsulation efficiency was found in the range of 57.14�0.47 to 88.57�0.799%, 54.78�0.76 to 83.55�0.65%, and 65.73�0.35 % to 95.04�0.42 respectively. The results of compatibility studies FTIR, PXRD, DSC and accelerated stability studies showed that no chemical interaction with drug and excipients. The dermal observation of skin irritation study shows no sign of either erythema or edema after 24 hrs of application. In % inhibition was more in microsponges gel as compare with pure drug gel in anti- inflammatory activity. Formulation of lornoxicam microsponges provides better control over release of drug. This study presents a new approach based on microsponge drug delivery system for topical application. 108 pp. Englisch. N� de r�f. du vendeur 9786202519199

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DEVELOPMENT OF LORNXICAM MICROSPONGES GEL FOR TOPICAL APPLICATION : LORNXICAM MICROSPONGES GEL

Harinath More

Edit� par LAP LAMBERT Academic Publishing, 2020

ISBN 10 : 6202519193 ISBN 13 : 9786202519199

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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The aim of the present study was to prepare microsponges gel formulation containing lornixicam by quasi emulsion solvent diffusion method. Lornoxicam is a Non-steroidal anti-inflammatory drug used for the treatment of various inflammatory diseases. Microsponges were spherical, uniform in shape, between 19 to 136mim in diameter. The production yield, actual drug content and encapsulation efficiency was found in the range of 57.14�0.47 to 88.57�0.799%, 54.78�0.76 to 83.55�0.65%, and 65.73�0.35 % to 95.04�0.42 respectively. The results of compatibility studies FTIR, PXRD, DSC and accelerated stability studies showed that no chemical interaction with drug and excipients. The dermal observation of skin irritation study shows no sign of either erythema or edema after 24 hrs of application. In % inhibition was more in microsponges gel as compare with pure drug gel in anti- inflammatory activity. Formulation of lornoxicam microsponges provides better control over release of drug. This study presents a new approach based on microsponge drug delivery system for topical application. N� de r�f. du vendeur 9786202519199

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DEVELOPMENT OF LORNXICAM MICROSPONGES GEL FOR TOPICAL APPLICATION

Anilkumar Shinde|Harinath More

Edit� par LAP LAMBERT Academic Publishing, 2020

ISBN 10 : 6202519193 ISBN 13 : 9786202519199

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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Shinde AnilkumarDr. Anilkumar J. Shinde, M.Pharm Ph.D (Pharmacy) from Shivaji University, Kolhapur. He has twenty years experience in marketing, teaching & research.Presently he is working as Associate Professor in Pharmaceutics Depa. N� de r�f. du vendeur 385945692

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DEVELOPMENT OF LORNXICAM MICROSPONGES GEL FOR TOPICAL APPLICATION

Anilkumar Shinde

Edit� par LAP LAMBERT Academic Publishing Apr 2020, 2020

ISBN 10 : 6202519193 ISBN 13 : 9786202519199

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Vendeur : buchversandmimpf2000, Emtmannsberg, BAYE, Allemagne

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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -The aim of the present study was to prepare microsponges gel formulation containing lornixicam by quasi emulsion solvent diffusion method. Lornoxicam is a Non-steroidal anti-inflammatory drug used for the treatment of various inflammatory diseases. Microsponges were spherical, uniform in shape, between 19 to 136�m in diameter. The production yield, actual drug content and encapsulation efficiency was found in the range of 57.14�0.47 to 88.57�0.799%, 54.78�0.76 to 83.55�0.65%, and 65.73�0.35 % to 95.04�0.42 respectively. The results of compatibility studies FTIR, PXRD, DSC and accelerated stability studies showed that no chemical interaction with drug and excipients. The dermal observation of skin irritation study shows no sign of either erythema or edema after 24 hrs of application. In % inhibition was more in microsponges gel as compare with pure drug gel in anti- inflammatory activity. Formulation of lornoxicam microsponges provides better control over release of drug. This study presents a new approach based on microsponge drug delivery system for topical application.VDM Verlag, Dudweiler Landstra�e 99, 66123 Saarbr�cken 108 pp. Englisch. N� de r�f. du vendeur 9786202519199

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