Gastroretentive Dosage Form: Novel Approach to Drug Delivery: Development of a sustained release Gastroretentive dosage form of Captopril for effective management of hypertension - Couverture souple

Dhote, Kanika; Dhote, Vinod Kumar

Couverture souple

ISBN 10 : 6202523948 ISBN 13 : 9786202523943

Editeur : LAP LAMBERT Academic Publishing, 2020

Synopsis

Sustained drug delivery means not only prolonged duration of drug delivery, but also implies predictability and reproducibility of drug release kinetics. Most of the sustained release dosage forms (SRDF) are based on the polymers, which retard the drug release. Polymeric materials like natural acrylic and cellulose polymers have been used widely for this purpose. There are several types of gastro retentive system, but among of all these systems gastroretentive floating drug delivery system had major advantages. In this system the active content embedded in the dosage form and having a desired release mechanism with buoyancy on to the gastric fluid. These types of dosage form float in the gastric environment without effecting the gastric emptying rate and so the dosage form remain in the gastric environment for a longer period of time. During the floating stage the active content release from the dosage form at specified time and rate in the gastric environment. The objective of the work designed to develop sustained release tablets as gastrorentive drug delivery dosage form of a drug meant for the management of treat high blood pressure hypertension.

Détails de l'édition

• Éditeur: LAP LAMBERT Academic Publishing
• Date d'édition: 2020
• Langue: anglais
• ISBN 10: 6202523948
• ISBN 13: 9786202523943
• Reliure: Broché
• Nombre de pages: 72
• Coordonnées du fabricant: non disponible
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