Pinaverium sustained release matrix tablets for colonic drug delivery - Couverture souple

Jha, Sajal Kumar; Rakasi, Sushma

 
9786202554589: Pinaverium sustained release matrix tablets for colonic drug delivery
Couverture souple
ISBN 10 : 6202554584 ISBN 13 : 9786202554589
Editeur : LAP LAMBERT Academic Publishing, 2020

Synopsis

This book deals with the Development and Characterization of sustained matrix tablets of a novel drug Pinaverium using different polymers.To facilitate the pH-independent drug release of Pinaverium, pH modifying agents (buffering agents) were used. Colon targeted tablets were prepared in two steps. Initially core tablets were prepared then the tablets were coated with Ph dependent polymers. Eudragit RLPO and S100 were used as enteric coating polymers. The pre-compression mixture of all formulations was subjected to various flow property tests and each one the formulations were passed the tests. The tablets were coated by polymers and so the coated tablets were subjected to various evaluation techniques. The tablets were passed all the tests. Among all the formulations F6 formulation was found to be optimized as a result of it had the drug release of up to 12 hours and showed most of 98.45% drug release.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2020
Langue
anglais
ISBN 10 
6202554584
ISBN 13 
9786202554589
Reliure
Broché
Nombre de pages
68
Coordonnées du fabricant
non disponible
Personne responsable
KreGa Onlinehandel GmbH
4950000000000
info@krega-onlinehandel.de

Birkenweg 31
Brakel
33034
Allemagne