Targeted Metabolomics: Improved Detection and Quantification of Drugs: Small molecules - Targeted metabolomics approch - Couverture souple

Patel, Daxesh; Patel, Chirag; Shrivastav, Pranav

 
9786203041200: Targeted Metabolomics: Improved Detection and Quantification of Drugs: Small molecules - Targeted metabolomics approch
Couverture souple
ISBN 10 : 6203041203 ISBN 13 : 9786203041200
Editeur : LAP LAMBERT Academic Publishing, 2020

Synopsis

Pharmacokinetic and bio-equivalency studies require very precise and accurate assay methods that are well-validated to quantify drugs in biological samples. The assay methods have to be sensitive enough to determine the biological sample concentration of the drug and/or its metabolite(s) for a period of about five elimination half-lives after the dosage of the drug. The assay methods also have to be very selective to ensure reliable data, free from the interference of endogenous98 compounds in the biological samples. In addition, methods have to be as robust and cost-effective as possible, making of particular importance to bioequivalent studies. Above all, the assay methods must be able to withstand the inspection of national drug registration authorities who judge them on the basis of criteria established by worldwide harmony.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2020
Langue
anglais
ISBN 10 
6203041203
ISBN 13 
9786203041200
Reliure
Broché
Nombre de pages
276
Coordonnées du fabricant
non disponible
Personne responsable
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