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Process Development of Amlodipine and Olmesartan Medoxomil Tablets: Process Development of Amlodipine and Olmesartan Medoxomil Tablets 10/40 Mg - Couverture souple

Behera, Gayatri; Behera, Jayashree; Barik, Binapani

 
9786203409338: Process Development of Amlodipine and Olmesartan Medoxomil Tablets: Process Development of Amlodipine and Olmesartan Medoxomil Tablets 10/40 Mg
Couverture souple
ISBN 10 : 6203409332 ISBN 13 : 9786203409338
Editeur : LAP LAMBERT Academic Publishing, 2021

Synopsis

The present study was focused on process development of amlodipine and olmesartan medoxomil tablet 10/40mg. Amlodipine and Olmesartan medoxomil is a combination of a calcium channel blocker and an angiotensin II receptor antagonist used to treat high blood pressure . The Content uniformity was found of both the drugs were performed. Release study was conducted in pH 6.8 buffer media. Furthermore, dissolution profile comparison was carried out using similarity factor (f2) and the similarity factor of Amlodipine and Olmesartan Medoxomil found to be 73. Other studies Like DSC and FTIR studies reported compatibility of Amlodipine besylate with excipients like Cross Carmel lose sodium was performed shows no chemical interaction between drug and excipients. Dissolution profile of Test and Reference standard found to be similar, Similarity factor (f2) is 73.

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Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2021
Langue
anglais
ISBN 10 
6203409332
ISBN 13 
9786203409338
Reliure
Broché
Nombre de pages
72
Coordonnées du fabricant
non disponible
Personne responsable
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