Synthesis and Biological Evaluation of N and S Based Heterocycles: New Synthetic Approaches to Nitrogen and Sulfur Based Heterocycles and Biological Assessment for Selected Analogs - Couverture souple

Trivikram Reddy, Gundala; Chinna Gangi Reddy, Nallagondu

 
9786203861211: Synthesis and Biological Evaluation of N and S Based Heterocycles: New Synthetic Approaches to Nitrogen and Sulfur Based Heterocycles and Biological Assessment for Selected Analogs
Couverture souple
ISBN 10 : 6203861219 ISBN 13 : 9786203861211
Editeur : LAP LAMBERT Academic Publishing, 2021

Synopsis

Nitrogen and sulfur heterocycles are recognized as “privileged medicinal scaffolds” because these compounds are found in a wide variety of bioactive natural products and pharmaceuticals. Among them, azoles (1,2 and 1,3-azoles) have been considered as an ‘important structural motif’ in a huge number of natural products and also in medicinally valuable compounds. Because of their broad based utility, efforts to develop green and sustainable synthetic methodologies for the synthesis of 1,2 and 1,3-azoles are on the ever-increasing trend in synthetic organic chemistry. In the present study, attempts have been made to develop new synthetic routes for the synthesis of benzo-fused 1,2-azoles (indazoles) and 1,3-azoles (benzimidazoles) and nitrogen and sulfur containing 1,3- azoles like thiazoles (i.e. 2-aminothiazoles and hydrazinyl-thiazoles). Further, biological activities (antioxidant, antimicrobial and anti-cancer) of the synthesized hydrazinyl-thiazole compounds have been investigated.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2021
Langue
anglais
ISBN 10 
6203861219
ISBN 13 
9786203861211
Reliure
Broché
Nombre de pages
192
Coordonnées du fabricant
non disponible
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