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Synopsis
Alzheimer's disease (AD), is a chronic neurodegenerative disease that causes senile decay of neurons It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. Genetic factors such as rare variants of TREM2(triggering receptor expressed on myeloid cells-2) strongly increase the risk of developing AD, confirming the role of microglia in AD pathogenesis. In the last 5 years, several studies have dissected the mechanisms by which TREM2, as well as its rare variants affect amyloid and tau pathologies and their consequences in both animal models and in human studies. In this review, we summarize increases in our understanding of the involvement of TREM2 and microglia in AD development that may open new therapeutic strategies targeting the immune system to influence AD pathogenesis.
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Trem-2 And Its Role In Alzheimer¿s
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LAP LAMBERT Academic Publishing Jun 2021, 2021
ISBN 10 : 6203926523
ISBN 13 : 9786203926521
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Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne
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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Alzheimer's disease (AD), is a chronic neurodegenerative disease that causes senile decay of neurons It is the cause of 60-70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. Genetic factors such as rare variants of TREM2(triggering receptor expressed on myeloid cells-2) strongly increase the risk of developing AD, confirming the role of microglia in AD pathogenesis. In the last 5 years, several studies have dissected the mechanisms by which TREM2, as well as its rare variants affect amyloid and tau pathologies and their consequences in both animal models and in human studies. In this review, we summarize increases in our understanding of the involvement of TREM2 and microglia in AD development that may open new therapeutic strategies targeting the immune system to influence AD pathogenesis. 60 pp. Englisch. N° de réf. du vendeur 9786203926521
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Trem-2 And Its Role In Alzheimer's : and Other Neurodegenerative Disorders
Edité par
LAP LAMBERT Academic Publishing, 2021
ISBN 10 : 6203926523
ISBN 13 : 9786203926521
Neuf
Taschenbuch
Vendeur : AHA-BUCH GmbH, Einbeck, Allemagne
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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Alzheimer's disease (AD), is a chronic neurodegenerative disease that causes senile decay of neurons It is the cause of 60-70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. Genetic factors such as rare variants of TREM2(triggering receptor expressed on myeloid cells-2) strongly increase the risk of developing AD, confirming the role of microglia in AD pathogenesis. In the last 5 years, several studies have dissected the mechanisms by which TREM2, as well as its rare variants affect amyloid and tau pathologies and their consequences in both animal models and in human studies. In this review, we summarize increases in our understanding of the involvement of TREM2 and microglia in AD development that may open new therapeutic strategies targeting the immune system to influence AD pathogenesis. N° de réf. du vendeur 9786203926521
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Trem-2 And Its Role In Alzheimer\ s
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ISBN 13 : 9786203926521
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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Kumar DileepDr. Dileep Kumar is an Assistant Professor at Poona College of Pharmacy, Pune. He did his B.Pharm from Manipal University Manipal. Dr. D. Kumar completed his Ph.D. from IIT(BHU) Varanasi. He has published many internation. N° de réf. du vendeur 490936212
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Trem-2 And Its Role In Alzheimer's
Edité par
LAP LAMBERT Academic Publishing Jun 2021, 2021
ISBN 10 : 6203926523
ISBN 13 : 9786203926521
Neuf
Taschenbuch
Vendeur : buchversandmimpf2000, Emtmannsberg, BAYE, Allemagne
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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Alzheimer's disease (AD), is a chronic neurodegenerative disease that causes senile decay of neurons It is the cause of 60-70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. Genetic factors such as rare variants of TREM2(triggering receptor expressed on myeloid cells-2) strongly increase the risk of developing AD, confirming the role of microglia in AD pathogenesis. In the last 5 years, several studies have dissected the mechanisms by which TREM2, as well as its rare variants affect amyloid and tau pathologies and their consequences in both animal models and in human studies. In this review, we summarize increases in our understanding of the involvement of TREM2 and microglia in AD development that may open new therapeutic strategies targeting the immune system to influence AD pathogenesis.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 60 pp. Englisch. N° de réf. du vendeur 9786203926521
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Trem-2 And Its Role In Alzheimer's | and Other Neurodegenerative Disorders
Edité par
LAP LAMBERT Academic Publishing, 2021
ISBN 10 : 6203926523
ISBN 13 : 9786203926521
Neuf
Taschenbuch
Vendeur : preigu, Osnabrück, Allemagne
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Taschenbuch. Etat : Neu. Trem-2 And Its Role In Alzheimer's | and Other Neurodegenerative Disorders | Dileep Kumar (u. a.) | Taschenbuch | Englisch | 2021 | LAP LAMBERT Academic Publishing | EAN 9786203926521 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. N° de réf. du vendeur 120395616
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