Mycophenolate Tablets to Prevent Immune Rejection of Transplants: Studies on Novel Mycophenolate Sodium Enteric Tablets to Prevent Immune rejection of Organ Transplants - Couverture souple

Rajesh Kumar, Putta

 
9786203926774: Mycophenolate Tablets to Prevent Immune Rejection of Transplants: Studies on Novel Mycophenolate Sodium Enteric Tablets to Prevent Immune rejection of Organ Transplants
Couverture souple
ISBN 10 : 6203926779 ISBN 13 : 9786203926774
Editeur : LAP LAMBERT Academic Publishing, 2021

Synopsis

Immunosuppressive therapy aims to prevent acute rejection and optimise the function of the transplanted organ. Mycophenolate sodium is a secondary metabolite produced by Penicillium brevicompactum, which has antibiotic and immunosuppressive properties used to prevent rejection of kidney transplants. It Inhibits inosine monophosphate dehydrogenase (IMPDH) and blocks the generation of guanosine nucleotides in the de novo pathway of DNA synthesis in the T cell. It is administered orally, at a recommended dose of 1.44 g per day. Mycophenolate sodium is available in 180-mg and 360-mg tablets. An enteric-coated formulation of Mycophenolate sodium is being developed and is currently in Phase IV clinical trial. This book provides insights on formulation development and in vitro evaluation aspects of Mycophenolate sodium enteric tablets which include HPLC analytical method development, compatibility studies, formulation development, evaluation of dosage forms, drug release and stability studies.

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Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2021
Langue
anglais
ISBN 10 
6203926779
ISBN 13 
9786203926774
Reliure
Broché
Nombre de pages
68
Coordonnées du fabricant
non disponible
Personne responsable
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