Self Micro Emulsifying Drug Delivery System: Formulation & Evaluation of Supersaturable Dry Microemulsion for the Enhancement of Dissolution - Couverture souple
Synopsis
Supersaturable SMEDDS appeared to be an interesting approach to alleviate problems associated with oral delivery of Nebivolol. This can be achieved by using NEB-SMEDDS having the formula as Castor oil (30 %,v/v), Tween-80 (35 %,v/v), PEG-400 (35 %,v/v) and HPMC(5%)was successfully optimized to achieve higher release as well as bioavailability of NEB in F8 formulation of SMEDDS in comparison to plain drug suspension. Stability of the formulation was confirmed by thermodynamic stability study and long term stability study. The release and bioavailability from F8 SMEDDS was increased due to presence of drugs in lipidic micro form as well as in dissolved state.In this book, the solid SMEDDS of NEB was prepared by adsorption method, using Aerosil-200 as adsorbent. The solid SMEDDS consisted of well-separated particles with smooth surface and preserved the self-emulsification performance of the liquid SMEDDS. The DSC study shows that NEB S-SMEDDS may be in the dissolved state. In-vitro dissolution test showed that the solid SMEDDS had a faster in vitro release rate than the plain drug suspension NEB.
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Self Micro Emulsifying Drug Delivery System
Edité par
LAP LAMBERT Academic Publishing Aug 2021, 2021
ISBN 10 : 6204197924
ISBN 13 : 9786204197920
Neuf
Taschenbuch
Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Supersaturable SMEDDS appeared to be an interesting approach to alleviate problems associated with oral delivery of Nebivolol. This can be achieved by using NEB-SMEDDS having the formula as Castor oil (30 %,v/v), Tween-80 (35 %,v/v), PEG-400 (35 %,v/v) and HPMC(5%)was successfully optimized to achieve higher release as well as bioavailability of NEB in F8 formulation of SMEDDS in comparison to plain drug suspension. Stability of the formulation was confirmed by thermodynamic stability study and long term stability study. The release and bioavailability from F8 SMEDDS was increased due to presence of drugs in lipidic micro form as well as in dissolved state.In this book, the solid SMEDDS of NEB was prepared by adsorption method, using Aerosil-200 as adsorbent. The solid SMEDDS consisted of well-separated particles with smooth surface and preserved the self-emulsification performance of the liquid SMEDDS. The DSC study shows that NEB S-SMEDDS may be in the dissolved state. In-vitro dissolution test showed that the solid SMEDDS had a faster in vitro release rate than the plain drug suspension NEB. 80 pp. Englisch. N° de réf. du vendeur 9786204197920
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Self Micro Emulsifying Drug Delivery System
Edité par
LAP LAMBERT Academic Publishing, 2021
ISBN 10 : 6204197924
ISBN 13 : 9786204197920
Neuf
Couverture souple
Vendeur : moluna, Greven, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Chede PallaviMrs. Pallavi K. Chede is working as Assistant Professor, at RSM s NN Sattha College of Pharmacy Ahmednagar(Maharashtra). She has 4 years of teaching and 2.5 years of industry experience. Mrs. Pallavi has an excellent tra. N° de réf. du vendeur 510073407
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Expédition depuis Allemagne vers Etats-Unis
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Self Micro Emulsifying Drug Delivery System
Edité par
LAP LAMBERT Academic Publishing Aug 2021, 2021
ISBN 10 : 6204197924
ISBN 13 : 9786204197920
Neuf
Taschenbuch
Vendeur : buchversandmimpf2000, Emtmannsberg, BAYE, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Supersaturable SMEDDS appeared to be an interesting approach to alleviate problems associated with oral delivery of Nebivolol. This can be achieved by using NEB-SMEDDS having the formula as Castor oil (30 %,v/v), Tween-80 (35 %,v/v), PEG-400 (35 %,v/v) and HPMC(5%)was successfully optimized to achieve higher release as well as bioavailability of NEB in F8 formulation of SMEDDS in comparison to plain drug suspension. Stability of the formulation was confirmed by thermodynamic stability study and long term stability study. The release and bioavailability from F8 SMEDDS was increased due to presence of drugs in lipidic micro form as well as in dissolved state.In this book, the solid SMEDDS of NEB was prepared by adsorption method, using Aerosil-200 as adsorbent. The solid SMEDDS consisted of well-separated particles with smooth surface and preserved the self-emulsi¿cation performance of the liquid SMEDDS. The DSC study shows that NEB S-SMEDDS may be in the dissolved state. In-vitro dissolution test showed that the solid SMEDDS had a faster in vitro release rate than the plain drug suspension NEB.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 80 pp. Englisch. N° de réf. du vendeur 9786204197920
Acheter neuf
EUR 39,90
Expédition à EUR 60
Expédition depuis Allemagne vers Etats-Unis
Expédition depuis Allemagne vers Etats-Unis
Quantité disponible : 1 disponible(s)
Image fournie par le vendeur
Self Micro Emulsifying Drug Delivery System : Formulation & Evaluation of Supersaturable Dry Microemulsion for the Enhancement of Dissolution
Edité par
LAP LAMBERT Academic Publishing, 2021
ISBN 10 : 6204197924
ISBN 13 : 9786204197920
Neuf
Taschenbuch
Vendeur : AHA-BUCH GmbH, Einbeck, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Supersaturable SMEDDS appeared to be an interesting approach to alleviate problems associated with oral delivery of Nebivolol. This can be achieved by using NEB-SMEDDS having the formula as Castor oil (30 %,v/v), Tween-80 (35 %,v/v), PEG-400 (35 %,v/v) and HPMC(5%)was successfully optimized to achieve higher release as well as bioavailability of NEB in F8 formulation of SMEDDS in comparison to plain drug suspension. Stability of the formulation was confirmed by thermodynamic stability study and long term stability study. The release and bioavailability from F8 SMEDDS was increased due to presence of drugs in lipidic micro form as well as in dissolved state.In this book, the solid SMEDDS of NEB was prepared by adsorption method, using Aerosil-200 as adsorbent. The solid SMEDDS consisted of well-separated particles with smooth surface and preserved the self-emulsification performance of the liquid SMEDDS. The DSC study shows that NEB S-SMEDDS may be in the dissolved state. In-vitro dissolution test showed that the solid SMEDDS had a faster in vitro release rate than the plain drug suspension NEB. N° de réf. du vendeur 9786204197920
Acheter neuf
EUR 40,89
Expédition à EUR 60,69
Expédition depuis Allemagne vers Etats-Unis
Expédition depuis Allemagne vers Etats-Unis
Quantité disponible : 1 disponible(s)