Articles liés à Quantification of DNA and AgNORs: correlating to cyclin...

Quantification of DNA and AgNORs: correlating to cyclin D1-immunoexpression in human breast cancer - Couverture souple

Assem Hamed, Mahmoud

 
9786204725413: Quantification of DNA and AgNORs: correlating to cyclin D1-immunoexpression in human breast cancer
Couverture souple
ISBN 10 : 6204725416 ISBN 13 : 9786204725413
Editeur : LAP LAMBERT Academic Publishing, 2021

Synopsis

Assessment of cell proliferation through the evaluation of cyclin D1, AgNORs, and DNA content provides a promising approach to the prognosis of breast cancer. Therefore, this work aimed to evaluate the prognostic significance of AgNORs and DNA image cytometry, and their relation to cyclin D1 immunoreactivity in breast cancer. This study was carried out on 50 prospective biopsies taken from patients with breast tumor. They were divided into control (10 cases) and benign (10 cases) as well as malignant (30 cases) groups. Computer-assisted image analysis cytometry is applied to evaluate the count of positive reactions of AgNORs and cyclin D1, and an integrated optical density (IOD) technique is used to quantify DNA content in the tissues stained by Feulgen stain and to assess the density of cyclin D1 immunoreactivity.

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Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2021
Langue
anglais
ISBN 10 
6204725416
ISBN 13 
9786204725413
Reliure
Broché
Nombre de pages
52
Coordonnées du fabricant
non disponible
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