PHYTOCHEMICAL AND PHARMACOLOGICAL ASSESSMENT OF LEUCAS ASPERA: Anticancer Activity of Leucas Aspera - Couverture souple

Swaminathan, Gomathi; Jupudi, Srikanth; Rajagopal, Kalirajan

 
9786204726298: PHYTOCHEMICAL AND PHARMACOLOGICAL ASSESSMENT OF LEUCAS ASPERA: Anticancer Activity of Leucas Aspera
Couverture souple
ISBN 10 : 6204726293 ISBN 13 : 9786204726298
Editeur : LAP LAMBERT Academic Publishing, 2022

Synopsis

Traditional Indian medicinal herbs have been used in the treatment of different diseases in the country for centuries. There have been claims that some traditional healers can successfully treat cancer using herbal drugs. The whole plant of Leucas aspera (Willd.) Link was selected and authenticated for the present study on the basis of ethnobotanical information. The present study concluded that the phytoconstituent was isolated from the whole plant of ethanol extract of Leucas aspera (Willd.) Link and characterized systematically with IR, H1 NMR and mass spectroscopy. The spectral data's of the isolated compound suggested that EELA I showed the structural similarities with Apigenin. Ethanol extract of Leucas aspera (Willd.) Link was screened for in vitro anticancer activities in three different cell lines such as HeLa, Hep G2 and MCF-7 by MTT assay method. HepG2 produced more significant in vitro anticancer activity than other two cell lines. The present study concluded that the antioxidant potentials like flavonoids, saponins present in extract might be responsible for the anticancer activities.

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Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2022
Langue
anglais
ISBN 10 
6204726293
ISBN 13 
9786204726298
Reliure
Broché
Nombre de pages
84
Coordonnées du fabricant
non disponible
Personne responsable
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