Self Micro-Emulsifying Mouth Dissolving Film: Design, Development and Evaluation - Couverture souple

Desai, Neha D.; Patel, Naziya R.; Dhole, Rani S.

 
9786204752211: Self Micro-Emulsifying Mouth Dissolving Film: Design, Development and Evaluation
Couverture souple
ISBN 10 : 6204752219 ISBN 13 : 9786204752211
Editeur : LAP LAMBERT Academic Publishing, 2022

Synopsis

Self-micro emulsifying mouth dissolving film is a new dosage form, an integration of self-micro emulsifying drug delivery system in a fast mouth dissolving film. Self micro emulsifying drug delivery system(SMEDDS) is an isotropic mixture of oil, surfactant, and co-surfactant. Upon mild agitation followed by dilution in an aqueous medium (gastrointestinal fluids), this system can form fine oil-in-water (o/w) microemulsion. Due to their small droplet size, they can provide a large surface area of absorption and improve the oral bioavailability of drugs more than any other drug delivery system. The composition of SMEDDS improves the solubility of poorly water-soluble drugs in an aqueous medium. Fast mouth dissolving films are complex polymeric matrices that can disintegrate/dissolve in the mouth within a short time. After dissolution, the drug gets available in the oral cavity for buccal mucosa absorption and reaches the systemic circulation without undergoing presystemic metabolism of the drug. These also have some advantages over other oral formulations including convenience to transport and store.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2022
Langue
anglais
ISBN 10 
6204752219
ISBN 13 
9786204752211
Reliure
Broché
Nombre de pages
96
Coordonnées du fabricant
non disponible
Personne responsable
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