Expression and functions of ROR alpha in the vascular system - Couverture souple

BESNARD, Sandrine

 
9786206076377: Expression and functions of ROR alpha in the vascular system
Couverture souple
ISBN 10 : 6206076377 ISBN 13 : 9786206076377
Editeur : Our Knowledge Publishing, 2023

Synopsis

Like other physiological systems, the development, structure and function of the vascular system are under the control of multiple nuclear receptors. However, very few studies have been carried out on the involvement of orphan nuclear receptors in the vascular system.The aim of this work was to study the expression and regulation of RORα, which belongs to this superfamily of orphan nuclear receptors, in vascular cells and whole vessels, and then to highlight some of its functional roles in the vascular system.The present work provides for the first time new data on the vascular phenotype of staggerer mice with a mutation in RORα. In particular, we have demonstrated that RORα plays an important role in blood pressure control and is involved in post-ischemic angiogenesis.

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Éditeur
Our Knowledge Publishing
Date d'édition
2023
Langue
anglais
ISBN 10 
6206076377
ISBN 13 
9786206076377
Reliure
Broché
Nombre de pages
128
Coordonnées du fabricant
non disponible
Personne responsable
non disponible