DEVELOPMENT AND VALIDATION OF HPLC METHOD OF ROSUVASTATIN SODIUM: Analytical method of Rosuvastatin Sodium - Couverture souple

Verma, Prabhakar

 
9786206146506: DEVELOPMENT AND VALIDATION OF HPLC METHOD OF ROSUVASTATIN SODIUM: Analytical method of Rosuvastatin Sodium
Couverture souple
ISBN 10 : 6206146502 ISBN 13 : 9786206146506
Editeur : LAP LAMBERT Academic Publishing, 2023

Synopsis

For the analysis of Rosuvastatin calcium, a specific and uncomplicated HPLC method was devised and validated. Rosuvastatin calcium belongs to the statin family, which is a reductase inhibitor for 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA). The medication is used to treat hypertension and ischemic coronary artery disease. It is also used to treat dyslipidemia and aid in the reduction of "bad cholesterol" levels. The technique was carried out on a C18 Column (250 4.6mm 1.d; 5) in isocratic mode with the mobile phase acetonitrile and water in the ratio 75:25 v/v. The wavelength is 242 nm, and the flow rate is 0.6 milliliters per minute.The linearity was discovered between 10 and 60µg/ml, with a correlation coefficient of 0.9998. The medication has a 3.643 retention time. Because the suggested method is simple, quick, accurate, precise, and repeatable, it can be used for routine quality control analysis of rosuvastatin in both pure and tablet dosage forms.

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Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2023
Langue
anglais
ISBN 10 
6206146502
ISBN 13 
9786206146506
Reliure
Broché
Nombre de pages
56
Coordonnées du fabricant
non disponible
Personne responsable
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