Articles liés à MANNICH BASE: A VERSATILE PHARMACOPHORE IN DRUG DESIGN...

MANNICH BASE: A VERSATILE PHARMACOPHORE IN DRUG DESIGN AND DISCOVERY - Couverture souple

Raju, Senthil Kumar; Sekar, Praveen

 
9786206738220: MANNICH BASE: A VERSATILE PHARMACOPHORE IN DRUG DESIGN AND DISCOVERY
Couverture souple
ISBN 10 : 6206738221 ISBN 13 : 9786206738220
Editeur : LAP LAMBERT Academic Publishing, 2023

Synopsis

Mannich bases are beta-amino ketone-carrying compounds that are the end products of the Mannich reaction. The Mannich reaction is a carbon-carbon bond-forming nucleophilic addition reaction that is used in the synthesis of many natural products, pharmaceuticals, and other substances. There are several aminoalkyl chain bearing Mannich bases with high curative value, such as fluoxetine, atropine, ethacrynic acid, trihexyphenidyl, and many others. The literature reveals that Mannich bases are highly reactive and have been shown to have potent anti-inflammatory, anticancer, antifilarial, antibacterial, antifungal, anticonvulsant, anthelmintic, antitubercular, analgesic, anti-HIV, antimalarial, antipsychotic, antiviral activities, anti-lipase activity, and so on properties. Thus, this book will be useful for understanding the various aspects of Mannich bases and it will be helpful for designing novel Mannich base derivatives in the future.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2023
Langue
anglais
ISBN 10 
6206738221
ISBN 13 
9786206738220
Reliure
Broché
Nombre de pages
76
Coordonnées du fabricant
non disponible
Personne responsable
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