Comparative Study Between Serology And Nucleic Acid Tests: In Blood Donors From The Hematology And Hemotherapy Center Of The State Of Piaui - Couverture souple

Valença Queiroz, Marcela De Lacerda; Queiroz Coelho, Alexandre; Amaral De Moraes, Maria Elisabete

Couverture souple

ISBN 10 : 6207113861 ISBN 13 : 9786207113866

Editeur : Our Knowledge Publishing, 2024

Synopsis

Serological tests for HIV and HCV are based on the detection of antibodies present in the donor's blood. This is what is known as the immunological window, a period in which, even if infected, the individual's serology is negative. The aim was to carry out a comparative study with a critical analysis of the screening methodologies for HIV and HCV testing in donors at the Hematology and Hemotherapy Center of the State of Piauí - HEMOPI. The comparison between the methodologies showed that although the agreement between the HIV tests was 99.7% and that between the HCV tests was 99.8%, the two methodologies are complementary, since the Kappa coefficients were 0.25 (fair) and 0.50 (moderate) respectively. In this way, it can be inferred that, as there are still no serological tests on the world market with 100% sensitivity and specificity, an alternative proposed to guarantee transfusion safety is the association between complementary methodologies, as is currently suggested by the Ministry of Health, through Health Surveillance.Keywords: Hemotherapy, HIV, HCV, Serology, NAT test.

Détails de l'édition

• Éditeur: Our Knowledge Publishing
• Date d'édition: 2024
• Langue: anglais
• ISBN 10: 6207113861
• ISBN 13: 9786207113866
• Reliure: Broché
• Nombre de pages: 52
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible