Isolation of verbascoside and validation of an analytical method: Method for standardizing the crude extract of the aerial parts of Buddleja stachyoides Cham. & Schltdl. (Scrophulariaceae) - Couverture souple

Soares De Oliveira, Daniella Maria; D. Miguel, Marilis; G. Miguel, Obdúlio

 
9786207238231: Isolation of verbascoside and validation of an analytical method: Method for standardizing the crude extract of the aerial parts of Buddleja stachyoides Cham. & Schltdl. (Scrophulariaceae)
Couverture souple
ISBN 10 : 6207238230 ISBN 13 : 9786207238231
Editeur : Our Knowledge Publishing, 2024

Synopsis

In this study, the phenylpropanoid verbascoside, identified by NMR, which has pharmacological activities such as antioxidant, analgesic, anti-inflammatory and gastroprotective, was isolated from the ethyl acetate fraction of the aerial parts of Buddleja stachyoides Cham. & Schltdl. The analytical method using high-performance liquid chromatography was developed and validated to quantify the verbascoside content present in the crude alcoholic extract of the aerial parts. It proved to be reliable, sensitive, precise, simple and low-cost, as well as meeting all the validation parameters required by ANVISA's RE No. 899 of May 29, 2003. A long-chain fatty acid, identified as triacontanoic acid, was also isolated from the hexane fraction of B. stachyoides roots. This book is aimed at health professionals and researchers and offers them a contribution to research, development and the production chain of herbal medicines and/or pharmaceutical products based on extracts from B. stachyoides, or any other plant species containing the substance verbascoside.

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Éditeur
Our Knowledge Publishing
Date d'édition
2024
Langue
anglais
ISBN 10 
6207238230
ISBN 13 
9786207238231
Reliure
Broché
Nombre de pages
56
Coordonnées du fabricant
non disponible
Personne responsable
non disponible