Tumor Microenvironment: Deciphering Tumor Microenvironment for Predicting Outcomes in Head and Neck Cancer - Couverture souple

Sankar NS, Roshna; Verma, Saloni; Gupta, Shalini

 
9786207476527: Tumor Microenvironment: Deciphering Tumor Microenvironment for Predicting Outcomes in Head and Neck Cancer
Couverture souple
ISBN 10 : 6207476522 ISBN 13 : 9786207476527
Editeur : LAP LAMBERT Academic Publishing, 2024

Synopsis

The document systematically explores the tumor microenvironment (TME) within the context of head and neck squamous cell carcinoma (HNSCC), elucidating its multifaceted nature and profound influence on cancer progression and treatment outcomes. Firstly, it delineates the various components constituting the TME, ranging from cellular elements such as cancer-associated fibroblasts, vascular endothelial cells, immune cells (macrophages, neutrophils, lymphocytes, mast cells, natural killer cells), and platelets, to the extracellular matrix and cancer stem cells. This comprehensive overview underscores the complexity of the TME and highlights the diverse interactions among its constituents. Furthermore, the document delves into the role of the TME at different stages of HNSCC pathogenesis, elucidating its involvement in premalignant lesion development and primary tumor progression. It also examines the molecular crosstalk between genetic and epigenetic alterations and their impact on shaping the TME in HNSCC, providing insights into the underlying mechanisms driving cancer aggressiveness.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2024
Langue
anglais
ISBN 10 
6207476522
ISBN 13 
9786207476527
Reliure
Broché
Nombre de pages
88
Coordonnées du fabricant
non disponible
Personne responsable
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