UV Spectroscopic Method and Method Validation of Methylphenidate: UV Spectroscopic Method and Method Validation of Methylphenidate in Bulk and Marketed Dosage Form Economically - Couverture souple

Choudhury, Tirthankar; Chaurasiya, Jay; Gupta, Ashwani

 
9786207488346: UV Spectroscopic Method and Method Validation of Methylphenidate: UV Spectroscopic Method and Method Validation of Methylphenidate in Bulk and Marketed Dosage Form Economically
Couverture souple
ISBN 10 : 6207488342 ISBN 13 : 9786207488346
Editeur : LAP LAMBERT Academic Publishing, 2024

Synopsis

This UV-spectrophotometric technique is quite simple, accurate, precise,reproducible, and sensitive. The UV method has been developed for quantification of Methylphenidate in tablet formulation. It involves absorbance measurement at 288 nm (ʎmax of Methylphenidate) in Ethanol and distilled water (89:11) ratio. For the UV Spectrophotometric method, linearity was obtained in a concentration range of 1-50µg/ml for methylphenidate and with a regression value of 0.9998. Recovery was found in the range of 98-101%. The standard deviation and % RSD were found to be < 2 %. It showed the high precision of the method, in accordance with ICH guidelines. The method has been successively applied to active pharmaceutical ingredients and was validated according to ICH guidelines. The method is highly accurate, reproducible and economical.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2024
Langue
anglais
ISBN 10 
6207488342
ISBN 13 
9786207488346
Reliure
Broché
Nombre de pages
72
Coordonnées du fabricant
non disponible
Personne responsable
KreGa Onlinehandel GmbH
4950000000000
info@krega-onlinehandel.de

Birkenweg 31
Brakel
33034
Allemagne