VITAMIN D STATUS IN ASTHMATIC CHILDREN - Couverture souple

Khalsi, Fatma

Couverture souple

ISBN 10 : 6207673255 ISBN 13 : 9786207673254

Editeur : Our Knowledge Publishing, 2024

Synopsis

Asthma in children is the most common respiratory disease worldwide. It is a major cause of morbidity and mortality. An accurate assessment of its prevalence has been hampered by the heterogeneity of asthma definitions. It has been described that vitamin D possesses an immunomodulatory effect via its receptor (VDR) and 1-alpha-hydroxylase, which are present in T and B lymphocytes, macrophages and antigen-presenting cells. Thus, 25 hydroxy-vitamin D (25 OH D) reduces the proliferation of T lymphocytes (particularly Thelper-1 [Th1] and Th17 lymphocytes) and the production of certain "pro-inflammatory" cytokines (particularly Il-2, Il-6 and IFN-γ), and it has also been described that the vitamin reduces mainly viral respiratory infections and improves lung function. The interaction between asthma and vitamin D has been studied over the past two decades. This interaction is multi-faceted and has potential clinical implications for asthmatic patients, affecting disease severity, control and prognosis.

Détails de l'édition

• Éditeur: Our Knowledge Publishing
• Date d'édition: 2024
• Langue: anglais
• ISBN 10: 6207673255
• ISBN 13: 9786207673254
• Reliure: Broché
• Nombre de pages: 52
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible