Cytotoxicity and Genotoxicity Analysis of Two Endondontic Cements: in human fibroblast cultures in vitro - Couverture souple

De Paiva Macedo, Camila

 
9786207756711: Cytotoxicity and Genotoxicity Analysis of Two Endondontic Cements: in human fibroblast cultures in vitro
Couverture souple
ISBN 10 : 6207756711 ISBN 13 : 9786207756711
Editeur : Our Knowledge Publishing, 2024

Synopsis

The aim of this in vitro study was to evaluate the cytotoxic and genotoxic potential of MTA Fillapex endodontic cement compared to AH plus cement. Human fibroblast cell lines FG11 and FG15 were used for this study. Cytotoxicity and genotoxicity were analyzed in human gingival fibroblasts subjected to conditioned cell culture medium by MTT reduction assay and micronucleus formation test respectively. Cells cultured in DMEM medium served as a control. Cell viability was measured at 24, 48 and 72 hours. The results were analyzed using Biostat 4.0. The Shapiro Wilk normality test was performed and the sample showed non-normal behavior. A descriptive analysis was carried out and the results were submitted to the Kruskal-Wallis (Dunn) test. All the cements and the control group showed lower MTT values at 24 hours compared to 48 and 72 hours (p<0.05). Greater cell viability was observed in AH Plus cement and the control group compared to MTA Fillapex in all experimental periods (p≤0.0002).

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Éditeur
Our Knowledge Publishing
Date d'édition
2024
Langue
anglais
ISBN 10 
6207756711
ISBN 13 
9786207756711
Reliure
Broché
Nombre de pages
56
Coordonnées du fabricant
non disponible
Personne responsable
non disponible