Articles liés à HIF-1 AS A POTENTIAL DRUG TARGET FOR SOLID TUMORS

HIF-1 AS A POTENTIAL DRUG TARGET FOR SOLID TUMORS - Couverture souple

Manohar, Sonal; Majithiya, Kinjal; Guralwar, Palak

 
9786208010676: HIF-1 AS A POTENTIAL DRUG TARGET FOR SOLID TUMORS
Couverture souple
ISBN 10 : 6208010675 ISBN 13 : 9786208010676
Editeur : LAP LAMBERT Academic Publishing, 2024

Synopsis

Hypoxia is a typical microenvironmental characteristic of many solid tumors. HIF-1 is the key regulator of growing tumor's response to hypoxia. HIF-1α subunit levels rise in hypoxic environments, when oncogenes are activated, and/or when tumor suppressor genes are inactivated, this is necessary for HIF-1 function in tumors. HIF-1 turns on genes that enable cells of a solid tumor to flourish in the noxious hypoxic tumor environment via attainment of numerous cancer hallmarks. This book elaborates the regulation and role of HIF-1 in oncogenic signalling. Further, its potential as a drug target for solid tumors is also discussed. The book will be useful as a reference book for students of graduate and post-graduate level courses in Life Science, Biomedical Science as well as to those who have a special interest in Cancer Biology.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2024
Langue
anglais
ISBN 10 
6208010675
ISBN 13 
9786208010676
Reliure
Broché
Nombre de pages
100
Coordonnées du fabricant
non disponible
Personne responsable
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