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Synthesis, Antioxidant and Antimicrobial Activity of New Thiophene: Thiophene containing antimicrobial and antioxidant compound - Couverture souple

Devi, Manisha; Arora, Kaushal; Verma, Prabhakar Kumar

 
9786208065805: Synthesis, Antioxidant and Antimicrobial Activity of New Thiophene: Thiophene containing antimicrobial and antioxidant compound
Couverture souple
ISBN 10 : 6208065801 ISBN 13 : 9786208065805
Editeur : LAP LAMBERT Academic Publishing, 2025

Synopsis

In the current scenario, the Gewald synthesis mechanism was used to synthesize a series of 11 newly designed thiophene analogs (D1-D11) derivatives using (Scheme-1, D1-D11). FTIR, 1H-NMR are used for the characterization of the newly synthesized analogs. After structural characterization, these derivatives are then screened for their in vitro biological evaluation. The biological evaluation of designed thiophene analogs was performed to test their antibacterial, antifungal and antioxidant action. Among all the designed and synthesized analogs, compounds D11 and D6 exhibit strong antibacterial action against Escherichia coli and Bacillus subtilis. Compound D3 and D11 has the strongest antifungal properties towards Aspergillus clavatus Compound D3 and D11 produces the greatest antioxidant activity with an IC50 value of 51.18 and 49.60.

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Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2025
Langue
anglais
ISBN 10 
6208065801
ISBN 13 
9786208065805
Reliure
Broché
Nombre de pages
92
Coordonnées du fabricant
non disponible
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