Articles liés à MOLECULAR DOCKING STUDIES OF MOA-B INHIBITORS: Monoamine...

MOLECULAR DOCKING STUDIES OF MOA-B INHIBITORS: Monoamine oxidase inhibitor docking - Couverture souple

Singh, Rahul; Tripathi, Avinash C.

 
9786208417109: MOLECULAR DOCKING STUDIES OF MOA-B INHIBITORS: Monoamine oxidase inhibitor docking
Couverture souple
ISBN 10 : 6208417104 ISBN 13 : 9786208417109
Editeur : LAP LAMBERT Academic Publishing, 2024

Synopsis

The present study was aimed at molecular docking studies of known inhibitors of MAO protein is to understand the binding interactions between the inhibitor and the enzyme at a molecular level. All Candidates from the database were selected as potential leads against MAO -B enzyme. The structural diversity has been observed in the compounds. The high affinity of the ligand Befloxatone is attributed to its four binding interactions at the active site of the protein. And other compounds also shows good binding energy. Thus, the obtained hits could be treated as good leads in the design of potent inhibitors of MAO- B enzyme, most commonly found to be expressed in the Parkinson's patients.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Éditeur
LAP LAMBERT Academic Publishing
Date d'édition
2024
Langue
anglais
ISBN 10 
6208417104
ISBN 13 
9786208417109
Reliure
Broché
Nombre de pages
52
Coordonnées du fabricant
non disponible
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